The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Syntrophic exchange in synthetic microbial communities
Open accessAbstract
Significance: Metabolic exchange between microbes is a crucial process driving the development of microbial ecosystems. The exchange of essential amino acids presents an opportunity to investigate the guiding principles underlying microbial trade in nature. In this study, we devised synthetic communities of Escherichia coli bacteria of increasing complexity to measure general properties enabling metabolic exchange of amino acids. We identified numerous syntrophic interactions that enable cooperative growth, which exhibited both positive and negative epistasis with increasing community complexity. Our results suggest that amino acid auxotrophy may be an evolutionarily optimizing strategy to reduce biosynthetic burden while promoting cooperative interactions between different bacteria in the microbiome.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Programming cells by multiplex genome engineering and accelerated evolution
Wang, H. H., Isaacs, F. J., Carr, P. A., Sun, Z. Z., Xu, G., Forest, C. R., & Church, G. M. (2009) · Nature · doi:10.1038/nature08187 · Cited by 1,529 · cited 1×
“coli derivative of MG1655, which carried an integrated, temperatureinducible, λ-Red prophage for recombineering (37).”
BackgroundSelf-citation
Cited by
Core microbiomes for sustainable agroecosystems
Toju, H., Peay, K. G., Yamamichi, M., Narisawa, K., Hiruma, K., Naito, K., Fukuda, S., Ushio, M., Nakaoka, S., Onoda, Y., et al. (2018) · Nature Plants · doi:10.1038/s41477-018-0139-4 · Cited by 1,077
Modifying and reacting to the environmental pH can drive bacterial interactions
Ratzke, C., & Gore, J. (2018) · PLOS Biology · doi:10.1371/journal.pbio.2004248 · Cited by 455
Sun, X., Xu, Z., Xie, J., Hesselberg-Thomsen, V., Tan, T., Zheng, D., Strube, M. L., Dragoš, A., Shen, Q., Zhang, R., et al. (2022) · The ISME Journal · doi:10.1038/s41396-021-01125-3 · Cited by 455
Yeast Creates a Niche for Symbiotic Lactic Acid Bacteria through Nitrogen Overflow
Ponomarova, O., Gabrielli, N., Sévin, D. C., Mülleder, M., Zirngibl, K., Bulyha, K., Andrejev, S., Kafkia, E., Typas, A., Sauer, U., et al. (2017) · Cell Systems · doi:10.1016/j.cels.2017.09.002 · Cited by 409
Soil microbiome: a key player for conservation of soil health under changing climate
Dubey, A., Malla, M. A., Khan, F., Chowdhary, K., Yadav, S., Kumar, A., Sharma, S., Khare, P. K., & Khan, M. L. (2019) · Biodiversity and Conservation · doi:10.1007/s10531-019-01760-5 · Cited by 396
Metadata
- Authors
- Mee, M. T., Collins, J. J., Church, G. M., & Wang, H. H.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2014-04-28
- Volume
- 111
- Issue
- 20
- Pages
- E2149-56
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2029945156
- Cited by
- 616
- References
- 1
- FWCI
- 11.19
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Syntrophic exchange in synthetic microbial communities. https://app.cochat.ai/papers/10.1073/pnas.1405641111
- The paper
- Mee, M. T., Collins, J. J., Church, G. M., & Wang, H. H. (2014). Syntrophic exchange in synthetic microbial communities. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1405641111
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
