The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
A Mitofusin-2–dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver
Open accessAbstract
Significance: We provide, to our knowledge, the first in vivo quantitative description of the adaptive response of the mitochondrial reticulum to the metabolic transition occurring in the liver in the hours after feeding. When nutrients become limiting, mitochondria size, cristae density, and respiratory capacity drop, but mitochondria–ER contacts, which control calcium and lipids fluxes between these organelles, double. A proteolytic inactivation of Optic atrophy 1 (Opa1), a major regulator of fusion and cristae architecture, accompanies these changes and found to depend on Mitofusin-2, a key regulator of mitochondria–ER contact biogenesis. Thus, mitochondria adapt to nutrient depletion by coupling the molecular machineries that organize cristae architecture and mitochondria–ER contact assembly, which were previously thought to operate independently of each other.
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OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion
Frezza, C., Cipolat, S., Martins de Brito, O., Micaroni, M., Beznoussenko, G. V., Rudka, T., Bartoli, D., Polishuck, R. S., Danial, N. N., De Strooper, B., et al. (2006) · Cell · doi:10.1016/j.cell.2006.06.025 · Cited by 1,673
Cogliati, S., Frezza, C., Soriano, M. E., Varanita, T., Quintana-Cabrera, R., Corrado, M., Cipolat, S., Costa, V., Casarin, A., Gomes, L. C., et al. (2013) · Cell · doi:10.1016/j.cell.2013.08.032 · Cited by 1,265
Morita, M., Gravel, S.-P., Chénard, V., Sikström, K., Zheng, L., Alain, T., Gandin, V., Avizonis, D., Arguello, M., Zakaria, C., et al. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.10.001 · Cited by 842
The i -AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission
Anand, R., Wai, T., Baker, M. J., Kladt, N., Schauss, A. C., Rugarli, E., & Langer, T. (2014) · Journal of Cell Biology · doi:10.1083/jcb.201308006 · Cited by 812
Sebastián, D., Hernández-Alvarez, M. I., Segalés, J., Sorianello, E., Muñoz, J. P., Sala, D., Waget, A., Liesa, M., Paz, J. C., Gopalacharyulu, P., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1108220109 · Cited by 673
The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice
Wakabayashi, J., Zhang, Z., Wakabayashi, N., Tamura, Y., Fukaya, M., Kensler, T. W., Iijima, M., & Sesaki, H. (2009) · Journal of Cell Biology · doi:10.1083/jcb.200903065 · Cited by 667
mTORC1 controls fasting-induced ketogenesis and its modulation by ageing
Sengupta, S., Peterson, T. R., Laplante, M., Oh, S., & Sabatini, D. M. (2010) · Nature · doi:10.1038/nature09584 · Cited by 646
Self-citationInducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells
Head, B., Griparic, L., Amiri, M., Gandre-Babbe, S., & van der Bliek, A. M. (2009) · Journal of Cell Biology · doi:10.1083/jcb.200906083 · Cited by 515
Davies, V. J., Hollins, A. J., Piechota, M. J., Yip, W., Davies, J. R., White, K. E., Nicols, P. P., Boulton, M. E., & Votruba, M. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm079 · Cited by 449
Cited by
Mitochondrial Cristae: Where Beauty Meets Functionality
Cogliati, S., Enriquez, J. A., & Scorrano, L. (2016) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2016.01.001 · Cited by 816
Coming together to define membrane contact sites
Scorrano, L., De Matteis, M. A., Emr, S., Giordano, F., Hajnóczky, G., Kornmann, B., Lackner, L. L., Levine, T. P., Pellegrini, L., Reinisch, K., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09253-3 · Cited by 730
Self-citationCritical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether
Naon, D., Zaninello, M., Giacomello, M., Varanita, T., Grespi, F., Lakshminaranayan, S., Serafini, A., Semenzato, M., Herkenne, S., Hernández-Alvarez, M. I., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1606786113 · Cited by 521
Calcium and mitochondria in the regulation of cell death
Orrenius, S., Gogvadze, V., & Zhivotovsky, B. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.01.137 · Cited by 526
Mitochondrial diseases: the contribution of organelle stress responses to pathology
Suomalainen, A., & Battersby, B. J. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.66 · Cited by 505
Metadata
- Authors
- Sood, A., Jeyaraju, D. V., Prudent, J., Caron, A., Lemieux, P., McBride, H. M., Laplante, M., Tóth, K., & Pellegrini, L.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2014-10-28
- Volume
- 111
- Issue
- 45
- Pages
- 16017-16022
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2011393200
- Cited by
- 171
- References
- 11
- FWCI
- 5.23
- Type
- journal article
- Language
- en
- Open access
- green
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- Sood, A., Jeyaraju, D. V., Prudent, J., Caron, A., Lemieux, P., McBride, H. M., Laplante, M., Tóth, K., & Pellegrini, L. (2014). A Mitofusin-2–dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1408061111
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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