Carlactone is converted to carlactonoic acid by MAX1 in Arabidopsis and its methyl ester can directly interact with AtD14 in vitro
Open accessAbstract
Significance: Strigolactones (SLs) are plant hormones that inhibit shoot branching and are parasitic and symbiotic signals toward root parasitic plants and arbuscular mycorrhizal fungi, respectively. Therefore, the manipulation of SL levels potentially improves the yield of crops. To achieve this goal, the biosynthesis pathway of SLs must be fully understood. SLs are biosynthesized from a precursor, named carlactone (CL), which is derived from carotenoid. However, no downstream pathway of CL has been elucidated. In this study, we show that CL is converted into a carboxylated metabolite, named carlactonoic acid, by Arabidopsis MAX1, the enzymatic function of which had been unknown, and that its methyl ester has the ability to interact with a SL receptor and suppress shoot branching in Arabidopsis .
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There are hints for the interaction of a carlactonic acid methyl ester with the putative SL receptor AtD14.
“The same authors reported hints for the interaction of a carlactonic acid methyl ester with the putative SL receptor AtD14 (see SL signaling discussion below; Abe et al., 2014).”
From Shaping plant architecture (2015) · cites this paper as Abe et al., 2014
Carlactone is converted to carlactonic acid by the action of MAX1 in Arabidopsis.
“They demonstrated that carlactone is converted to carlactonic acid by the action of MAX1 in Arabidopsis.”
From Shaping plant architecture (2015) · cites this paper as Abe et al., 2014
Cites
Molecular mechanism of strigolactone perception by DWARF14
Nakamura, H., Xue, Y.-L., Miyakawa, T., Hou, F., Qin, H.-M., Fukui, K., Shi, X., Ito, E., Ito, S., Park, S.-H., et al. (2013) · Nature Communications · doi:10.1038/ncomms3613 · Cited by 378 · see citing works
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Teichmann, T., & Muhr, M. (2015) · Frontiers in Plant Science · doi:10.3389/fpls.2015.00233 · Cited by 228 · see citing works
“The same authors reported hints for the interaction of a carlactonic acid methyl ester with the putative SL receptor AtD14 (see SL signaling discussion below; Abe et al., 2014).”
Background
- Authors
- Abe, S., Sado, A., Tanaka, K., Kisugi, T., Asami, K., Ota, S., Kim, H. I., Yoneyama, K., Xie, X., Ohnishi, T., Seto, Y., Yamaguchi, S., Akiyama, K., Yoneyama, K., & Nomura, T.
- Affiliations
- Department of Bioproductive Science, Graduate School of Agriculture, and
- Osaka Prefecture University (JP)
- Tohoku University (JP)
- Tokyo University of Agriculture and Technology (JP)
- Utsunomiya University (JP)
- Shizuoka University (JP)
- ORCID
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2014-11-25
- Volume
- 111
- Issue
- 50
- Pages
- 18084-18089
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC4273391
- OpenAlex
- W2021842921
- Cited by
- 425
- References
- 1
- Citations by year
- 2026: 20 · 2025: 32 · 2024: 43 · 2023: 39 · 2022: 45 · 2021: 42 · 2020: 45 · 2019: 34 · 2018: 31 · 2017: 44 · 2016: 27 · 2015: 22 · 2014: 1
- FWCI
- 36.63
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Education, Culture, Sports, Science, and Technology (MEXT) (23380061, 24114010)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Parasitism and Resistance
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Allelopathy and phytotoxic interactions
- Keywords
- strigolactones, MAX1, carotenoid cleavage dioxygenase, DWARF14, strigolactone receptors, carotenoid biosynthesis, Arabidopsis thaliana, cytochrome P450 monooxygenase
- MeSH terms
- Carboxylic Acids, Chromatography, Liquid, Cloning, Molecular, Escherichia coli, Esters, Genetic Vectors, Lactones, Plant Growth Regulators, Yeasts, Arabidopsis, Plant Shoots, Arabidopsis Proteins, Tandem Mass Spectrometry, Biosynthetic Pathways
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