The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Microdroplet fusion mass spectrometry for fast reaction kinetics
Open accessAbstract
Significance: Time-resolved mass spectrometry is a powerful approach for identifying reaction intermediates and measuring reaction kinetics, yet one critical limitation is temporal resolution. Here, we describe microdroplet fusion mass spectrometry on timescales as short as microseconds. In our approach, two high-speed streams of liquid microdroplets collide to make fused droplets of 13 ± 6 μm in diameter, where the reactants are mixed in a negligible time. After a short flying time of 50 μs or less during which the reaction proceeds, the fused droplets enter a mass spectrometer for chemical analysis of intermediates and reaction products. This enables observation of early events of various fast chemical reactions in the liquid phase.
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Cites
An Algorithm for Least-Squares Estimation of Nonlinear Parameters
Marquardt, D. W. (1963) · Journal of the Society for Industrial and Applied Mathematics · doi:10.1137/0111030 · Cited by 30,728
Accelerated Hantzsch electrospray synthesis with temporal control of reaction intermediates
Bain, R. M., Pulliam, C. J., & Cooks, R. G. (2015) · Chemical Science · doi:10.1039/c4sc02436b · Cited by 230
In situ observation of peptide bond formation at the water-air interface
Griffith, E. C., & Vaida, V. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1210029109 · Cited by 184
Cited by
Spontaneous Generation of Hydrogen Peroxide from Aqueous Microdroplets
Lee, J. K., Walker, K. L., Han, H. S., Kang, J., Prinz, F. B., Waymouth, R. M., Nam, H. G., & Zare, R. N. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1911883116 · Cited by 717
Self-citationAccelerated Reaction Kinetics in Microdroplets: Overview and Recent Developments
Wei, Z., Li, Y., Cooks, R. G., & Yan, X. (2020) · Annual Review of Physical Chemistry · doi:10.1146/annurev-physchem-121319-110654 · Cited by 631
Organic Reactions in Microdroplets: Reaction Acceleration Revealed by Mass Spectrometry
Yan, X., Bain, R. M., & Cooks, R. G. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201602270 · Cited by 583
Abiotic production of sugar phosphates and uridine ribonucleoside in aqueous microdroplets
Nam, I., Lee, J. K., Nam, H. G., & Zare, R. N. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1714896114 · Cited by 262
Self-citationSpontaneous formation of gold nanostructures in aqueous microdroplets
Lee, J. K., Samanta, D., Nam, H. G., & Zare, R. N. (2018) · Nature Communications · doi:10.1038/s41467-018-04023-z · Cited by 253
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Metadata
- Authors
- Lee, J. K., Kim, S., Nam, H. G., & Zare, R. N.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2015-03-16
- Volume
- 112
- Issue
- 13
- Pages
- 3898-3903
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2049745495
- Cited by
- 268
- References
- 3
- FWCI
- 10.33
- Type
- journal article
- Language
- en
- Open access
- green
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