Cited by 638Innovative Microfluidic and Catalytic Techniques InnovationMass Spectrometry Techniques and ApplicationsFluid Dynamics and Heat Transfer

The DOI matches its Crossref record; 122 of the 122 references it cites were found in a registry or an index.

Accelerated Reaction Kinetics in Microdroplets: Overview and Recent Developments

Open access
Wei, Zhenwei, Li, Yangjie, Cooks, R. Graham, Yan, Xin·2020·Annual Review of Physical Chemistry

Abstract

Various organic reactions, including important synthetic reactions involving C–C, C–N, and C–O bond formation as well as reactions of biomolecules, are accelerated when the reagents are present in sprayed or levitated microdroplets or in thin films. The reaction rates increase by orders of magnitude with decreasing droplet size or film thickness. The effect is associated with reactions at the solution–air interface. A key factor is partial solvation of the reagents at the interface, which reduces the critical energy for reaction. This phenomenon is of intrinsic interest and potentially of practical value as a simple, rapid method of performing small-scale synthesis.

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Crossref · 10.1146/annurev-physchem-121319-110654

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Metadata

Authors
Wei, Z., Li, Y., Cooks, R. G., & Yan, X.
Affiliations
  • Purdue University West Lafayette (US)
  • Texas A&M University (US)
Corresponding author
Yan, Xin
Venue
Annual Review of Physical Chemistry
Published
2020-04-20
Volume
71
Issue
1
Pages
31-51
ISSN
  • 0066-426X (ISSN-L)
  • 1545-1593
OpenAlex
W3017097444
Cited by
631
References
122
Citations by year
2026: 117 · 2025: 142 · 2024: 123 · 2023: 91 · 2022: 73 · 2021: 62 · 2020: 23
FWCI
5.21
Type
journal article
Language
en
Open access
Locations
  • Annual Review of Physical Chemistry (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Science Foundation (1905087)
  • Defense Advanced Research Projects Agency (1905087, W911NF-16-2-0020)
  • Advanced Research Projects Agency
Topics
  • Physical Sciences › Chemical Engineering › Fluid Flow and Transfer Processes › Innovative Microfluidic and Catalytic Techniques Innovation
  • Physical Sciences › Chemistry › Spectroscopy › Mass Spectrometry Techniques and Applications
  • Physical Sciences › Engineering › Computational Mechanics › Fluid Dynamics and Heat Transfer
Keywords
microdroplets, reaction kinetics, air/solution interface, levitated droplets, thin films, C–C bond formation, C–N bond formation, C–O bond formation, small-scale synthesis, reaction rate enhancement

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