The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Regenerative medicine: Current therapies and future directions
Open accessAbstract
Organ and tissue loss through disease and injury motivate the development of therapies that can regenerate tissues and decrease reliance on transplantations. Regenerative medicine, an interdisciplinary field that applies engineering and life science principles to promote regeneration, can potentially restore diseased and injured tissues and whole organs. Since the inception of the field several decades ago, a number of regenerative medicine therapies, including those designed for wound healing and orthopedics applications, have received Food and Drug Administration (FDA) approval and are now commercially available. These therapies and other regenerative medicine approaches currently being studied in preclinical and clinical settings will be covered in this review. Specifically, developments in fabricating sophisticated grafts and tissue mimics and technologies for integrating grafts with host vasculature will be discussed. Enhancing the intrinsic regenerative capacity of the host by altering its environment, whether with cell injections or immune modulation, will be addressed, as well as methods for exploiting recently developed cell sources. Finally, we propose directions for current and future regenerative medicine therapies.
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Hippo–YAP/TAZ signalling in organ regeneration and regenerative medicine
Moya, I. M., & Halder, G. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0086-y · Cited by 981
Hydrogel scaffolds for tissue engineering: the importance of polymer choice
Spicer, C. D. (2020) · Polymer Chemistry · doi:10.1039/c9py01021a · Cited by 527
Alginate and its application to tissue engineering
Sahoo, D. R., & Biswal, T. (2021) · SN Applied Sciences · doi:10.1007/s42452-020-04096-w · Cited by 517
Tissue Engineering and Regenerative Medicine: Achievements, Future, and Sustainability in Asia
Han, F., Wang, J., Ding, L., Hu, Y., Li, W., Yuan, Z., Guo, Q., Zhu, C., Yu, L., Wang, H., et al. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.00083 · Cited by 357
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Metadata
- Authors
- Mao, A. S., & Mooney, D. J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2015-11-23
- Volume
- 112
- Issue
- 47
- Pages
- 14452-14459
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2172957891
- Cited by
- 941
- References
- 9
- FWCI
- 45.14
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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