P hacking in biology: An open secret
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Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
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The use of statistical methods has been demonstrated to be suboptimal in some fields.
“The use of statistical methods has been demonstrated to be suboptimal in some fields.”
From How to design preclinical studies in nanomedicine and cell therapy to maximize the prospects of clinical translation (2018) · cites this paper as [23]
P-hacking has high prevalence.
“P-hacking22,23 (where investigators perform multiple analyses sequentially, for example by adding more samples or excluding some potential outliers until the desired thresholds of statistical significance are achieved)”
From How to design preclinical studies in nanomedicine and cell therapy to maximize the prospects of clinical translation (2018) · cites this paper as [23]
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Cites
Scientific method: Statistical errors
Nuzzo, R. (2014) · Nature · doi:10.1038/506150a · Cited by 1,536 · see citing works
Biotic interactions mediate soil microbial feedbacks to climate change
Crowther, T. W., Thomas, S. M., Maynard, D. S., Baldrián, P., Covey, K., Frey, S. D., van Diepen, L. T. A., & Bradford, M. A. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1502956112 · Cited by 262 · see citing works
Hararuk, O., Smith, M. J., & Luo, Y. (2014) · Global Change Biology · doi:10.1111/gcb.12827 · Cited by 118 · see citing works
Smith, R. A., Levine, T. R., Lachlan, K. A., & Fediuk, T. A. (2002) · Human Communication Research · doi:10.1111/j.1468-2958.2002.tb00821.x · Cited by 77 · see citing works
A call for statistical editors in ecology
von Wehrden, H., Schultner, J., & Abson, D. J. (2015) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2015.03.013 · Cited by 8 · see citing works
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Ioannidis, J. P. A., Kim, B. Y. S., & Trounson, A. (2018) · Nature Biomedical Engineering · doi:10.1038/s41551-018-0314-y · Cited by 175 · see citing works
- Authors
- Veresoglou, S. D.
- Affiliations
- Berlin Brandenburg Institute of Advanced Biodiversity Research (DE)
- Corresponding author
- Veresoglou, Stavros D.
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2015-08-25
- Volume
- 112
- Issue
- 37
- Pages
- E5112-3
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC4577170
- OpenAlex
- W2128309487
- Cited by
- 7
- References
- 5
- Citations by year
- 2022: 1 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 1 · 2015: 1
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion, other-oa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Dahlem Centre of Plant Sciences, Freie Universität Berlin (no designated grant)
- Topics
- Social Sciences › Safety Research › Academic integrity and plagiarism
- Social Sciences › Decision Sciences › Information Systems and Management › Academic Publishing and Open Access
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Keywords
- p-hacking, publication bias, statistical significance, research reproducibility, false positives, biology research
- MeSH terms
- Animals, Feedback, Fungi, Models, Theoretical, Soil Microbiology, Food Chain, Isopoda, Climate Change
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