The DOI matches its Crossref record.
Modulation of CTP:phosphocholine cytidylyltransferase by membrane curvature elastic stress
Open accessAbstract
The activity of CTP:phosphocholine cytidylyltransferase, a rate-limiting enzyme in phosphatidylcholine biosynthesis, is modulated by its interaction with lipid bilayers [Kent, C. (1997) Biochim. Biophys. Acta 1348, 79–90]. Its regulation is of central importance in the maintenance of membrane lipid homeostasis. Here we show evidence that the stored curvature elastic stress in the lipid membrane's monolayer modulates the activity of CTP:phosphocholine cytidylyltransferase. Our results show how a purely physical feedback signal could play a key role in the control of membrane lipid synthesis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Lipid landscapes and pipelines in membrane homeostasis
Holthuis, J. C. M., & Menon, A. K. (2014) · Nature · doi:10.1038/nature13474 · Cited by 901
Bigay, J., & Antonny, B. (2012) · Developmental Cell · doi:10.1016/j.devcel.2012.10.009 · Cited by 567
Biotechnologies for Marine Oil Spill Cleanup: Indissoluble Ties with Microorganisms
Mapelli, F., Scoma, A., Michoud, G., Aulenta, F., Boon, N., Borin, S., Kalogerakis, N., & Daffonchio, D. (2017) · Trends in Biotechnology · doi:10.1016/j.tibtech.2017.04.003 · Cited by 214
Phospholipid biosynthesis program underlying membrane expansion during B-lymphocyte differentiation
Fagone, P., Sriburi, R., Ward-Chapman, C., Frank, M., Wang, J., Gunter, C., Brewer, J. W., & Jackowski, S. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m608175200 · Cited by 93
Self-citation
Metadata
- Authors
- Attard, G. S., Templer, R. H., Smith, W. S., Hunt, A. N., & Jackowski, S.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2000-07-25
- Volume
- 97
- Issue
- 16
- Pages
- 9032-9036
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2141941251
- Cited by
- 264
- References
- 0
- FWCI
- 2.37
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Modulation of CTP:phosphocholine cytidylyltransferase by membrane curvature elastic stress. https://app.cochat.ai/papers/10.1073/pnas.160260697
- The paper
- Attard, G. S., Templer, R. H., Smith, W. S., Hunt, A. N., & Jackowski, S. (2000). Modulation of CTP:phosphocholine cytidylyltransferase by membrane curvature elastic stress. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.160260697
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
