The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.
Caenorhabditis elegans responses to bacteria from its natural habitats
Open accessAbstract
Significance: Caenorhabditis elegans is a major model organism, both from the pathogenesis dimension and also for metabolism, aging, and developmental biology perspectives. And yet, its natural ecology, most especially, its natural microbiome, is almost untouched. Here we establish the natural microbial community of C. elegans . Using extensive culture collections, we categorize its spectrum of responses (from antagonistic to beneficial) to a wide breadth of wild bacteria with nearly 80% of isolates supporting robust growth. In the wild, specific microbes correlate with the population state of the animals, which is supported by reconstruction experiments in the lab. Thus, a simplified natural community related to that found in the wild can now be studied in the laboratory for its impact on C. elegans physiology.
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Cited by
Qi, B., & Han, M. (2018) · Cell · doi:10.1016/j.cell.2018.07.032 · Cited by 164
Metadata
- Authors
- Samuel, B. S., Rowedder, H., Braendle, C., Félix, M.-A., & Ruvkun, G.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2016-06-17
- Volume
- 113
- Issue
- 27
- Pages
- E3941-9
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2433871124
- Cited by
- 409
- References
- 51
- FWCI
- 13.96
- Type
- journal article
- Language
- en
- Open access
- green
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