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Cited by 276

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Pseudomonas aeruginosa transcriptome during human infection

Open access
Cornforth, Daniel M., Dees, Justine L., Ibberson, Carolyn B., Huse, Holly K., Mathiesen, Inger H., Kirketerp-Møller, Klaus, Wolcott, Randy D., Rumbaugh, Kendra P., Bjarnsholt, Thomas, Whiteley, Marvin·2018·Proceedings of the National Academy of Sciences

Abstract

Significance: Microbiologists typically use laboratory systems to study the bacteria that infect humans. Over time, this has created a gap between what researchers understand about bacteria growing in the laboratory and those growing in humans. It is well-known that the behavior of bacteria is shaped by their environment, but how this behavior differs in laboratory models compared with human infections is poorly understood. We compared transcription data from a variety of human infections with data from a range of in vitro samples. We found important differences in expression of genes involved in antibiotic resistance, cell–cell communication, and metabolism. Understanding the bacterial expression patterns in human patients is a necessary step toward improved therapy and the development of more accurate laboratory models.

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Crossref · 10.1073/pnas.1717525115

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Metadata

Authors
Cornforth, D. M., Dees, J. L., Ibberson, C. B., Huse, H. K., Mathiesen, I. H., Kirketerp-Møller, K., Wolcott, R. D., Rumbaugh, K. P., Bjarnsholt, T., & Whiteley, M.
Venue
Proceedings of the National Academy of Sciences
Published
2018-05-14
Volume
115
Issue
22
Pages
E5125-E5134
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2804143592
Cited by
276
References
4
FWCI
9.73
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Pseudomonas aeruginosa transcriptome during human infection. https://app.cochat.ai/papers/10.1073/pnas.1717525115
The paper
Cornforth, D. M., Dees, J. L., Ibberson, C. B., Huse, H. K., Mathiesen, I. H., Kirketerp-Møller, K., Wolcott, R. D., Rumbaugh, K. P., Bjarnsholt, T., & Whiteley, M. (2018). Pseudomonas aeruginosa transcriptome during human infection. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1717525115

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.