The DOI matches its Crossref record.
Modifications of cellulose synthase confer resistance to isoxaben and thiazolidinone herbicides in Arabidopsis Ixr1 mutants
Open accessAbstract
In many higher plants, cellulose synthesis is inhibited by isoxaben and thiazolidinone herbicides such as 5-tert-butyl-carbamoyloxy-3-(3-trifluromethyl) phenyl-4-thiazolidinone. Semidominant mutations at the IXR1 and IXR2 loci of Arabidopsis confer isoxaben and thiazolidinone resistance. Isolation of the IXR1 gene by map-based cloning revealed that it encodes the AtCESA3 isoform of cellulose synthase. The two known mutant alleles contain point mutations that replace glycine 998 with aspartic acid, and threonine 942 with isoleucine, respectively. The mutations occur in a highly conserved region of the enzyme near the carboxyl terminus that is well separated from the proposed active site. Although the IXR1 gene is expressed in the same cells as the structurally related RSW1 ( AtCESA1 ) cellulose synthase gene, these two CESA genes are not functionally redundant.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Visualization of Cellulose Synthase Demonstrates Functional Association with Microtubules
Paredez, A. R., Somerville, C. R., & Ehrhardt, D. W. (2006) · Science · doi:10.1126/science.1126551 · Cited by 1,371
Self-citationThe Cell Biology of Cellulose Synthesis
McFarlane, H. E., Döring, A., & Persson, S. (2014) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-050213-040240 · Cited by 623
Desprez, T., Juraniec, M., Crowell, E. F., Jouy, H., Pochylova, Z., Parcy, F., Höfte, H., Gonneau, M., & Vernhettes, S. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706569104 · Cited by 616
Persson, S., Paredez, A., Carroll, A., Palsdottir, H., Doblin, M., Poindexter, P., Khitrov, N., Auer, M., & Somerville, C. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706592104 · Cited by 615
Self-citationHeisler, M. G., Hamant, O., Krupinski, P., Uyttewaal, M., Ohno, C., Jönsson, H., Traas, J., & Meyerowitz, E. M. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000516 · Cited by 459
Metadata
- Authors
- Scheible, W.-R., Eshed, R., Richmond, T., Delmer, D., & Somerville, C.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2001-08-21
- Volume
- 98
- Issue
- 18
- Pages
- 10079-10084
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1990652169
- Cited by
- 448
- References
- 0
- FWCI
- 21.19
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Modifications of cellulose synthase confer resistance to isoxaben and thiazolidinone herbicides in Arabidopsis Ixr1 mutants. https://app.cochat.ai/papers/10.1073/pnas.191361598
- The paper
- Scheible, W.-R., Eshed, R., Richmond, T., Delmer, D., & Somerville, C. (2001). Modifications of cellulose synthase confer resistance to isoxaben and thiazolidinone herbicides in Arabidopsis Ixr1 mutants. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.191361598
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
