The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Exhaled aerosol increases with COVID-19 infection, age, and obesity
Open accessAbstract
Significance: Superspreading events have distinguished the COVID-19 pandemic from the early outbreak of the disease. Our studies of exhaled aerosol suggest that a critical factor in these and other transmission events is the propensity of certain individuals to exhale large numbers of small respiratory droplets. Our findings indicate that the capacity of airway lining mucus to resist breakup on breathing varies significantly between individuals, with a trend to increasing with the advance of COVID-19 infection and body mass index multiplied by age (i.e., BMI-years). Understanding the source and variance of respiratory droplet generation, and controlling it via the stabilization of airway lining mucus surfaces, may lead to effective approaches to reducing COVID-19 infection and transmission.
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Cites
Superspreading and the effect of individual variation on disease emergence
Lloyd-Smith, J. O., Schreiber, S. J., Kopp, P. E., & Getz, W. M. (2005) · Nature · doi:10.1038/nature04153 · Cited by 2,514
Aerodynamic Analysis of SARS-CoV-2 in Two Wuhan Hospitals
Liu, Y., Ning, Z., Chen, Y., Guo, M., Liu, Y., Gali, N. K., Sun, L., Duan, Y., Cai, J., Westerdahl, D., et al. (2020) · Nature · doi:10.1038/s41586-020-2271-3 · Cited by 1,872
Fears, A. C., Klimstra, W. B., Duprex, P., Hartman, A., Weaver, S. C., Plante, K. C., Mirchandani, D., Plante, J. A., Aguilar, P. V., Fernández, D., et al. (2020) · doi:10.1101/2020.04.13.20063784 · Cited by 453
Self-citationPersistence of Severe Acute Respiratory Syndrome Coronavirus 2 in Aerosol Suspensions
Fears, A. C., Klimstra, W. B., Duprex, P., Hartman, A., Weaver, S. C., Plante, K. S., Mirchandani, D., Plante, J. A., Aguilar, P. V., Fernández, D., et al. (2020) · Emerging Infectious Diseases · doi:10.3201/eid2609.201806 · Cited by 453
Self-citationSattar, N., Ho, F. K., Gill, J. M., Ghouri, N., Gray, S. R., Celis-Morales, C. A., Katikireddi, S. V., Berry, C., Pell, J. P., McMurray, J. J., et al. (2020) · Diabetes & Metabolic Syndrome: Clinical Research & Reviews · doi:10.1016/j.dsx.2020.06.060 · Cited by 104
Cited by
Airborne transmission of respiratory viruses
Wang, C. C., Prather, K. A., Sznitman, J., Jimenez, J. L., Lakdawala, S. S., Tufekci, Z., & Marr, L. C. (2021) · Science · doi:10.1126/science.abd9149 · Cited by 1,543
Infectious SARS-CoV-2 Is Emitted in Aerosol Particles
Hawks, S. A., Prussin, A. J., Kuchinsky, S. C., Pan, J., Marr, L. C., & Duggal, N. K. (2021) · mBio · doi:10.1128/mbio.02527-21 · Cited by 57
Metadata
- Authors
- Edwards, D. A., Ausiello, D., Salzman, J., Devlin, T., Langer, R., Beddingfield, B. J., Fears, A. C., Doyle-Meyers, L. A., Redmann, R. K., Killeen, S. Z., Maness, N. J., & Roy, C. J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2021-02-09
- Volume
- 118
- Issue
- 8
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W3127661060
- Cited by
- 235
- References
- 5
- FWCI
- 27.38
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Edwards, D. A., Ausiello, D., Salzman, J., Devlin, T., Langer, R., Beddingfield, B. J., Fears, A. C., Doyle-Meyers, L. A., Redmann, R. K., Killeen, S. Z., Maness, N. J., & Roy, C. J. (2021). Exhaled aerosol increases with COVID-19 infection, age, and obesity. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.2021830118
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
