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The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.

Biosilica formation in diatoms: Characterization of native silaffin-2 and its role in silica morphogenesis

Open access
Poulsen, Nicole, Sumper, Manfred, Kröger, Nils·2003·Proceedings of the National Academy of Sciences

Abstract

The biological formation of inorganic materials with complex form (biominerals) is a widespread phenomenon in nature, yet the molecular mechanisms underlying biomineral morphogenesis are not well understood. Among the most fascinating examples of biomineral structures are the intricately patterned, silicified cell walls of diatoms, which contain tightly associated organic macromolecules. From diatom biosilica a highly polyanionic phosphoprotein, termed native silaffin-2 (natSil-2), was isolated that carries unconventional amino acid modifications. natSil-2 lacked intrinsic silica formation activity but was able to regulate the activities of the previously characterized silica-forming biomolecules natSil-1A and long-chain polyamines. Combining natSil-2 and natSil-1A (or long-chain polyamines) generated an organic matrix that mediated precipitation of porous silica within minutes after the addition of silicic acid. Remarkably, the precipitate displayed pore sizes in the range 100–1000 nm, which is characteristic for diatom biosilica nanopatterns.

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Metadata

Authors
Poulsen, N., Sumper, M., & Kröger, N.
Venue
Proceedings of the National Academy of Sciences
Published
2003-09-24
Volume
100
Issue
21
Pages
12075-12080
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2088366997
Cited by
324
References
24
FWCI
9.64
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Biosilica formation in diatoms: Characterization of native silaffin-2 and its role in silica morphogenesis. https://app.cochat.ai/papers/10.1073/pnas.2035131100
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Poulsen, N., Sumper, M., & Kröger, N. (2003). Biosilica formation in diatoms: Characterization of native silaffin-2 and its role in silica morphogenesis. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.2035131100

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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