The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Biosilica formation in diatoms: Characterization of native silaffin-2 and its role in silica morphogenesis
Open accessAbstract
The biological formation of inorganic materials with complex form (biominerals) is a widespread phenomenon in nature, yet the molecular mechanisms underlying biomineral morphogenesis are not well understood. Among the most fascinating examples of biomineral structures are the intricately patterned, silicified cell walls of diatoms, which contain tightly associated organic macromolecules. From diatom biosilica a highly polyanionic phosphoprotein, termed native silaffin-2 (natSil-2), was isolated that carries unconventional amino acid modifications. natSil-2 lacked intrinsic silica formation activity but was able to regulate the activities of the previously characterized silica-forming biomolecules natSil-1A and long-chain polyamines. Combining natSil-2 and natSil-1A (or long-chain polyamines) generated an organic matrix that mediated precipitation of porous silica within minutes after the addition of silicic acid. Remarkably, the precipitate displayed pore sizes in the range 100–1000 nm, which is characteristic for diatom biosilica nanopatterns.
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Cites
Colorimetric Method for Determination of Sugars and Related Substances
DuBois, M., Gilles, K. A., Hamilton, J. K., Rebers, P. A., & Smith, F. (1956) · Analytical Chemistry · doi:10.1021/ac60111a017 · Cited by 52,269
Schägger, H., & von Jagow, G. (1987) · Analytical Biochemistry · doi:10.1016/0003-2697(87)90587-2 · Cited by 11,444
Lowenstam, H. A., & Weiner, S. (1989) · doi:10.1093/oso/9780195049770.001.0001 · Cited by 2,090
Higher‐Order Organization by Mesoscale Self‐Assembly and Transformation of Hybrid Nanostructures
Cölfen, H., & Mann, S. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200200562 · Cited by 1,816
Cooperative Formation of Inorganic-Organic Interfaces in the Synthesis of Silicate Mesostructures
Monnier, A., Schüth, F., Huo, Q., Kumar, D., Margolese, D., Maxwell, R. S., Stucky, G. D., Krishnamurty, M., Petroff, P., Firouzi, A., et al. (1993) · Science · doi:10.1126/science.261.5126.1299 · Cited by 1,569
Polycationic Peptides from Diatom Biosilica That Direct Silica Nanosphere Formation
Kröger, N., Deutzmann, R., & Sumper, M. (1999) · Science · doi:10.1126/science.286.5442.1129 · Cited by 1,409
Self-citationOverview of manual and automated DNA sequencing by the dideoxy chain termination method
CHEN, E., KUANG, W., & LEE, A. (1991) · Methods · doi:10.1016/s1046-2023(05)80158-6 · Cited by 833
Self-Assembly of Highly Phosphorylated Silaffins and Their Function in Biosilica Morphogenesis
Kröger, N., Lorenz, S., Brunner, E., & Sumper, M. (2002) · Science · doi:10.1126/science.1076221 · Cited by 792
Self-citationCha, J. N., Shimizu, K., Zhou, Y., Christiansen, S. C., Chmelka, B. F., Stucky, G. D., & Morse, D. E. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.2.361 · Cited by 786
Silicatein α: Cathepsin L-like protein in sponge biosilica
Shimizu, K., Cha, J., Stucky, G. D., & Morse, D. E. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.11.6234 · Cited by 714
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Controlling Mineral Morphologies and Structures in Biological and Synthetic Systems
Meldrum, F. C., & Cölfen, H. (2008) · Chemical Reviews · doi:10.1021/cr8002856 · Cited by 1,397
Protein- and Peptide-Directed Syntheses of Inorganic Materials
Dickerson, M. B., Sandhage, K. H., & Naik, R. R. (2008) · Chemical Reviews · doi:10.1021/cr8002328 · Cited by 960
Overview of microalgal extracellular polymeric substances (EPS) and their applications
Xiao, R., & Zheng, Y. (2016) · Biotechnology Advances · doi:10.1016/j.biotechadv.2016.08.004 · Cited by 938
Biological materials: Functional adaptations and bioinspired designs
Chen, P.-Y., McKittrick, J., & Meyers, M. A. (2012) · Progress in Materials Science · doi:10.1016/j.pmatsci.2012.03.001 · Cited by 766
Diatoms—From Cell Wall Biogenesis to Nanotechnology
Kröger, N., & Poulsen, N. (2008) · Annual Review of Genetics · doi:10.1146/annurev.genet.41.110306.130109 · Cited by 458
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Metadata
- Authors
- Poulsen, N., Sumper, M., & Kröger, N.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2003-09-24
- Volume
- 100
- Issue
- 21
- Pages
- 12075-12080
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2088366997
- Cited by
- 324
- References
- 24
- FWCI
- 9.64
- Type
- journal article
- Language
- en
- Open access
- green
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- Poulsen, N., Sumper, M., & Kröger, N. (2003). Biosilica formation in diatoms: Characterization of native silaffin-2 and its role in silica morphogenesis. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.2035131100
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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