The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells
Open accessAbstract
Recently, agonist antibodies to glucocorticoid-induced tumor necrosis factor receptor (GITR) (tumor necrosis factor receptor superfamily 18) have been shown to neutralize the suppressive activity of CD4+CD25+regulatory T cells. It was anticipated that this would be the role of the physiological ligand. We have identified and expressed the gene for mouse GITR ligand and have confirmed that its interaction with GITR reverses suppression by CD4+CD25+T cells. It also, however, provides a costimulatory signal for the antigen-driven proliferation of naïve T cells and polarized T helper 1 and T helper 2 clones. RT-PCR and mAb staining revealed mouse GITR ligand expression in dendritic cells, macrophages, and B cells. Expression was controlled by the transcription factor NF-1 and potentially by alternative splicing of mRNA destabilization sequences.
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A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
Black, R. A., Rauch, C. T., Kozlosky, C. J., Peschon, J. J., Slack, J. L., Wolfson, M. F., Castner, B. J., Stocking, K. L., Reddy, P., Srinivasan, S., et al. (1997) · Nature · doi:10.1038/385729a0 · Cited by 3,149
AU-rich elements: characterization and importance in mRNA degradation
Chen, C.-Y. A., & Shyu, A.-B. (1995) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)89102-1 · Cited by 1,948
CD4+CD25+ Immunoregulatory T Cells
McHugh, R. S., Whitters, M. J., Piccirillo, C. A., Young, D. A., Shevach, E. M., Collins, M., & Byrne, M. C. (2002) · Immunity · doi:10.1016/s1074-7613(02)00280-7 · Cited by 1,395
IL-10 Gene Expression Is Controlled by the Transcription Factors Sp1 and Sp3
Tone, M., Powell, M. J., Tone, Y., Thompson, S. A. J., & Waldmann, H. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.165.1.286 · Cited by 250
Self-citation
Cited by
Sakaguchi, S. (2005) · Nature Immunology · doi:10.1038/ni1178 · Cited by 2,669
Lutsiak, M. E. C., Semnani, R. T., De Pascalis, R., Kashmiri, S. V. S., Schlom, J., & Sabzevari, H. (2005) · Blood · doi:10.1182/blood-2004-06-2410 · Cited by 903
Dhabhar, F. S. (2009) · Neuroimmunomodulation · doi:10.1159/000216188 · Cited by 903
Helminth parasites – masters of regulation
Maizels, R. M., Balic, A., Gomez‐Escobar, N., Nair, M., Taylor, M. D., & Allen, J. E. (2004) · Immunological Reviews · doi:10.1111/j.0105-2896.2004.00191.x · Cited by 866
Mast cells are essential intermediaries in regulatory T-cell tolerance
Lu, L.-F., Lind, E. F., Gondek, D. C., Bennett, K. A., Gleeson, M. W., Pino-Lagos, K., Scott, Z. A., Coyle, A. J., Reed, J. L., Van Snick, J., et al. (2006) · Nature · doi:10.1038/nature05010 · Cited by 751
Metadata
- Authors
- Tone, M., Tone, Y., Adams, E., Yates, S. F., Frewin, M. R., Cobbold, S. P., & Waldmann, H.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2003-11-07
- Volume
- 100
- Issue
- 25
- Pages
- 15059-15064
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2139021664
- Cited by
- 345
- References
- 4
- FWCI
- 9.67
- Type
- journal article
- Language
- en
- Open access
- green
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- Tone, M., Tone, Y., Adams, E., Yates, S. F., Frewin, M. R., Cobbold, S. P., & Waldmann, H. (2003). Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.2334901100
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
