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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

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Mammalian Gene Collection (MGC) Program Team*·2002·Proceedings of the National Academy of Sciences

Abstract

The National Institutes of Health Mammalian Gene Collection (MGC) Program is a multiinstitutional effort to identify and sequence a cDNA clone containing a complete ORF for each human and mouse gene. ESTs were generated from libraries enriched for full-length cDNAs and analyzed to identify candidate full-ORF clones, which then were sequenced to high accuracy. The MGC has currently sequenced and verified the full ORF for a nonredundant set of >9,000 human and >6,000 mouse genes. Candidate full-ORF clones for an additional 7,800 human and 3,500 mouse genes also have been identified. All MGC sequences and clones are available without restriction through public databases and clone distribution networks (see http://mgc.nci.nih.gov ).

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Metadata

Authors
Mammalian Gene Collection (MGC) Program Team*
Venue
Proceedings of the National Academy of Sciences
Published
2002-12-11
Volume
99
Issue
26
Pages
16899-16903
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2108222684
Cited by
1,749
References
2
FWCI
41.69
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. https://app.cochat.ai/papers/10.1073/pnas.242603899
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Mammalian Gene Collection (MGC) Program Team*. (2002). Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.242603899

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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