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Cited by 274

The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

Ferritin-Conjugated Plant Agglutinins as Specific Saccharide Stains for Electron Microscopy: Application to Saccharides Bound to Cell Membranes

Open access
Nicolson, Garth L., Singer, S. J.·1971·Proceedings of the National Academy of Sciences

Abstract

An electron microscopic stain for specific saccharides was prepared by the conjugation of ferritin to concanavalin A, a plant agglutinin that specifically binds to oligosaccharides containing terminal d -glucose, d -mannose, or sterically related sugar residues. A technique was developed to allow topological visualization of erythrocyte and other membranes by means of transmission electron microscopy, and the distribution of the binding sites for ferritin-concanavalin A on such membrane preparations was determined. The conjugate was found to bind specifically to the outer, but not the inner, surface of erythrocyte membranes. The number of conjugate molecules bound per unit area of the membrane was larger for rabbit than for human erythrocytes.

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Crossref · 10.1073/pnas.68.5.942

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Metadata

Authors
Nicolson, G. L., & Singer, S. J.
Venue
Proceedings of the National Academy of Sciences
Published
1971-05
Volume
68
Issue
5
Pages
942-945
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2035219404
Cited by
274
References
12
FWCI
14.34
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Ferritin-Conjugated Plant Agglutinins as Specific Saccharide Stains for Electron Microscopy: Application to Saccharides Bound to Cell Membranes. https://app.cochat.ai/papers/10.1073/pnas.68.5.942
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Nicolson, G. L., & Singer, S. J. (1971). Ferritin-Conjugated Plant Agglutinins as Specific Saccharide Stains for Electron Microscopy: Application to Saccharides Bound to Cell Membranes. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.68.5.942

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.