The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Nonprotein Amino Acids from Spark Discharges and Their Comparison with the Murchison Meteorite Amino Acids
Open accessAbstract
All the nonprotein amino acids found in the Murchison meteorite are products of the action of electric discharge on a mixture of methane, nitrogen, and water with traces of ammonia. These amino acids include α-amino- n -butyric acid, α-aminoisobutyric acid, norvaline, isovaline, pipecolic acid, β-alanine, β-amino-n-butyric acid, β-aminoisobutyric acid, γ-aminobutyric acid, sarcosine, N -ethylglycine, and N -methylalanine. In addition, norleucine, alloisoleucine, N -propylglycine, N -isopropylglycine, N -methyl-β-alanine, N -ethyl-β-alanine α,β-diaminopropionic acid, isoserine, α,γ-diaminobutyric acid, and α-hydroxy-γ-aminobutyric acid are produced by the electric discharge, but have not been found in the meteorite.
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“Carbonaceous meteorites contain a myriad of organic compounds divided between a soluble fraction and an insoluble organic matter (IOM) phase consisting of intractable complex macromolecular organic material.”
From Polyesters as a Model System for Building Primitive Biologies from Non-Biological Prebiotic Chemistry (2020) · cites this paper as [11]
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Cites
A Production of Amino Acids Under Possible Primitive Earth Conditions
Miller, S. L. (1953) · Science · doi:10.1126/science.117.3046.528 · Cited by 3,522
Self-citationEvidence for Extraterrestrial Amino-acids and Hydrocarbons in the Murchison Meteorite
Kvenvolden, K. A., Lawless, J. G., Pering, K. L., Peterson, E., Flores, J. J. A., Ponnamperuma, C., Kaplan, I. R., & MOORE, C. B. (1970) · Nature · doi:10.1038/228923a0 · Cited by 867
On the Early Chemical History of the Earth and the Origin of Life
Urey, H. C. (1952) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.38.4.351 · Cited by 498
The mechanism of synthesis of amino acids by electric discharges
Miller, S. L. (1957) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(57)90366-9 · Cited by 380
Self-citationNonprotein Amino Acids in the Murchison Meteorite
Kvenvolden, K. A., Lawless, J. G., & Ponnamperuma, C. (1971) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.68.2.486 · Cited by 308
Cyanoacetylene in Prebiotic Synthesis
Sanchez, R. A., Ferris, J. P., & Orgel, L. E. (1966) · Science · doi:10.1126/science.154.3750.784 · Cited by 270
Amino Acid Analyses of the Murchison, Murray, and Allende Carbonaceous Chondrites
Cronin, J. R., & MOORE, C. B. (1971) · Science · doi:10.1126/science.172.3990.1327 · Cited by 245
Amino-acids, Aliphatic and Aromatic Hydrocarbons in the Murchison Meteorite
Oro, J. A., de Gibert, J. M., Lichtenstein, H. A., Wikström, S. A., & Flory, D. A. (1971) · Nature · doi:10.1038/230105a0 · Cited by 198
Prebiotic Synthesis of Hydrophobic and Protein Amino Acids
Ring, D., Wolman, Y., Friedmann, N., & Miller, S. L. (1972) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.69.3.765 · Cited by 194
Self-citationα-Aminonitriles formed by an electric discharge through a mixture of anhydrous methane and ammonia
Ponnamperuma, C., & Woeller, F. H. (1967) · Biosystems · doi:10.1016/0303-2647(67)90031-7 · Cited by 28
Determination of n-methylamino acids and their optical purity with an amino acid analyzer
Coggins, J. R., & Benoiton, N. L. (1970) · Journal of Chromatography A · doi:10.1016/s0021-9673(01)96572-0 · Cited by 22
Research works printed but not linked: 4
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- [8]Ring, D., Wolman, Y., Friedmann, N. & Miller, S. L. (1972) Proc. Nat. Acad. Sci. USA 69, 765–768.
- [13]Urey, H. C. (1952) Proc. Nat. Acad. Sci. USA 38, 351–363.
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Cited by
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Extraterrestrial Organic Compounds in Meteorites
Botta, O., & Bada, J. (2002) · Surveys in Geophysics · doi:10.1023/a:1020139302770 · Cited by 364
Organic Matter in Meteorites: Molecular and Isotopic Analyses of the Murchison Meteorite
Cronin, J. R., & Chang, S. (1993) · Springer eBooks · doi:10.1007/978-94-011-1936-8_9 · Cited by 386
The origin of life—a review of facts and speculations
Orgel, L. E. (1998) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(98)01300-0 · Cited by 367
Enrichment of the amino acid l -isovaline by aqueous alteration on CI and CM meteorite parent bodies
Glavin, D. P., & Dworkin, J. P. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811618106 · Cited by 307
Membranes and the Origin of Life: A Century of Conjecture
Deamer, D. W. (2016) · Journal of Molecular Evolution · doi:10.1007/s00239-016-9770-8 · Cited by 307
Metadata
- Authors
- Wolman, Y., Haverland, W. J., & Miller, S. L.
- Affiliations
- University of California San Diego (US)
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 1972-04
- Volume
- 69
- Issue
- 4
- Pages
- 809-811
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC426569
- OpenAlex
- W2006555521
- Cited by
- 198
- References
- 11
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 10 · 2023: 3 · 2022: 7 · 2021: 5 · 2020: 7 · 2019: 5 · 2018: 5 · 2017: 7 · 2016: 4 · 2015: 1 · 2014: 5 · 2013: 4 · 2012: 6
- FWCI
- 12.33
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science Foundation
- Topics
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Physical Sciences › Earth and Planetary Sciences › Space and Planetary Science › Astro and Planetary Science
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Space Science and Extraterrestrial Life
- Keywords
- nonprotein amino acids, Murchison meteorite, spark discharge, electric discharge synthesis, amino acid synthesis, prebiotic chemistry, GABA, N-methylalanine, pipecolic acid, beta-alanine, meteoritic amino acids
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