The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
The Wavelengths in Sunlight Effective in Producing Skin Cancer: A Theoretical Analysis
Open accessAbstract
DNA is taken as the target for skin cancer induced by ultraviolet light, and the known data on the sensitivity of DNA as a function of wavelength are summarized. The sun's spectrum at the surface of the earth and the DNA action spectrum are used to calculate the carcinogenic effectiveness as a function of wavelength. The most effective wavelengths at 30°N latitude are <305 nm, and a 1% change in atmospheric ozone results in a 2% change in the effective dose of ultraviolet light. Since both the basic biological and physical data are reasonably precise, the major requirement for a quantitative evaluation of the dose response relation for ultraviolet-induced skin cancer in man is better epidemiological data to compare with data from animal models.
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“In addition, relevant UVRinduced DNA damage markers such as cyclobutene pyrimidine dimers cannot be measured in SC tapes (Kraemer, 1997;Setlow, 1974).”
From Effect of Repeated Low-Dose UVR Exposure on Skin Inflammation Threshold, Skin Biomarkers, and Vitamin D in Healthy Adults (2025) · cites this paper as Setlow, 1974
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Ames, B. N., Durston, W. E., Yamasaki, E. F., & Lee, F. D. (1973) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.70.8.2281 · Cited by 2,279
Hart, R. W., & Setlow, R. B. (1974) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.71.6.2169 · Cited by 739
Self-citationPyrimidine dimers in ultraviolet-irradiated DNA’s
Setlow, R. B., & Carrier, W. L. (1966) · Journal of Molecular Biology · doi:10.1016/s0022-2836(66)80105-5 · Cited by 560
Self-citationPENETRATION OF EPIDERMIS BY ULTRAVIOLET RAYS
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The Biologic Effects of Ultraviolet Radiation
Everett, M. A. (1970) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1970.tb06009.x · Cited by 298
Effects of Radiation on Polynucleotides
Setlow, R. B., & Setlow, J. K. (1972) · Annual Review of Biophysics and Bioengineering · doi:10.1146/annurev.bb.01.060172.001453 · Cited by 221
Self-citationINDUCTION OF PYRIMIDINE DIMERS IN BACTERIAL DNA BY 365 nm RADIATION*
TYRRELL, R. M. (1973) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1973.tb06334.x · Cited by 203
DNA Damage and Repair in Light-Sensitive Human Skin Disease
Cleaver, J. E. (1970) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12280225 · Cited by 193
Bootsma, D., Mulder, M. P., Pot, F., & Cohen, J. A. (1970) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(70)90035-7 · Cited by 153
Stratospheric Ozone Depletion and Solar Ultraviolet Radiation on Earth
Cutchis, P. (1974) · Science · doi:10.1126/science.184.4132.13 · Cited by 122
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Cited by
Sorted by citations
A role for sunlight in skin-cancer – UV-induced p53 mutations in squamous-cell carcinoma
Brash, D. E., Rudolph, J. A., Simon, J. A., Lin, A., McKenna, G. J., Baden, H. P., Halperin, A. J., & Pontén, J. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.22.10124 · Cited by 1,959
Changes in biologically active ultraviolet radiation reaching the Earth's surface
Madronich, S., McKenzie, R. L., Björn, L. O., & Caldwell, M. M. (1998) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/s1011-1344(98)00182-1 · Cited by 1,086
Mutations induced by ultraviolet light
Pfeifer, G. P., You, Y., & Nia, A. B. (2005) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2004.06.057 · Cited by 798
Wavelengths effective in induction of malignant melanoma.
Setlow, R. B., Grist, E., Thompson, K. H., & Woodhead, A. D. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.14.6666 · Cited by 718
Self-citationChanges in biologically-active ultraviolet radiation reaching the Earth’s surface
McKenzie, R., Aucamp, P. J., Bais, A. F., Björn, L. O., & Ilyas, M. (2007) · Photochemical & Photobiological Sciences · doi:10.1039/b700017k · Cited by 650
Metadata
- Authors
- Setlow, R. B.
- Affiliations
- Oak Ridge National Laboratory (US)
- Corresponding author
- Setlow, R. B.
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 1974-09
- Volume
- 71
- Issue
- 9
- Pages
- 3363-3366
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC433772
- OpenAlex
- W2092873988
- Cited by
- 1,125
- References
- 20
- Citations by year
- 2026: 12 · 2025: 6 · 2024: 13 · 2023: 14 · 2022: 13 · 2021: 14 · 2020: 23 · 2019: 13 · 2018: 18 · 2017: 17 · 2016: 20 · 2015: 19 · 2014: 21 · 2013: 18 · 2012: 21
- FWCI
- 13.77
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Carcinogens and Genotoxicity Assessment
- Health Sciences › Medicine › Dermatology › Nonmelanoma Skin Cancer Studies
- Keywords
- ultraviolet radiation, skin cancer, solar spectrum, atmospheric ozone, dose-response relationship, UV-induced DNA damage, latitude effects
- MeSH terms
- DNA, Dose-Response Relationship, Radiation, Environmental Exposure, Models, Biological, Ozone, Photochemistry, Radiation Injuries, Skin Neoplasms, Sunlight, Ultraviolet Rays
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