Pyrimidine dimers in ultraviolet-irradiated DNA’s
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The molecular mechanisms of UV-induced apoptosis of keratinocytes include direct DNA damage (intrinsic).
“The molecular mechanisms of UV-induced apoptosis of keratinocytes include direct DNA damage (intrinsic), clustering of death receptors on the cell surface (extrinsic), and generation of ROS.”
From Molecular Mechanisms of UV-Induced Apoptosis and Its Effects on Skin Residential Cells: The Implication in UV-Based Phototherapy (2013) · cites this paper as [16]
UVB leads to two main photochemical reactions in DNA, including cyclobutane pyrimidine dimers and (6-4) pyrimidine-pyrimidone photoproducts.
“UVB leads to two main photochemical reactions in DNA, including cyclobutane pyrimidine dimers (CPDs) and (6–4) pyrimidine-pyrimidone photoproducts [(6–4)PPs] [15,16].”
From Molecular Mechanisms of UV-Induced Apoptosis and Its Effects on Skin Residential Cells: The Implication in UV-Based Phototherapy (2013) · cites this paper as [16]
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- Authors
- Setlow, R. B., & Carrier, W. L.
- Affiliations
- Oak Ridge National Laboratory (US)
- Venue
- Journal of Molecular Biology
- Publisher
- Elsevier BV
- Published
- 1966-05
- Volume
- 17
- Issue
- 1
- Pages
- 237-254
- ISSN
- 0022-2836 (ISSN-L)
- OpenAlex
- W2008512283
- Cited by
- 560
- References
- 0
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 3 · 2023: 3 · 2022: 8 · 2021: 10 · 2020: 5 · 2019: 11 · 2018: 6 · 2017: 12 · 2016: 9 · 2015: 7 · 2014: 12 · 2013: 12 · 2012: 1
- FWCI
- 13.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Molecular Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA and Nucleic Acid Chemistry
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Carcinogens and Genotoxicity Assessment
- Keywords
- pyrimidine dimers, UV irradiation, DNA photoproducts, thymine dimers, cytosine deamination, photoreactivation, DNA synthesis inhibition, Escherichia coli DNA, dose dependence
- MeSH terms
- Chromatography, Paper, DNA, Bacterial, Escherichia coli, Haemophilus influenzae, N-Glycosyl Hydrolases, Nucleotidyltransferases, Phosphoric Monoester Hydrolases, Pyrimidines, Radiation Effects, Staphylococcus, Ultraviolet Rays
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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