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The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Agrobacterium tumefaciens DNA and PS8 Bacteriophage DNA Not Detected in Crown Gall Tumors

Open access
Chilton, Mary-Dell, Currier, Thomas C., Farrand, Stephen K., Bendich, Arnold J., Gordon, Milton P., Nester, Eugene W.·1974·Proceedings of the National Academy of Sciences

Abstract

Renaturation kinetics of labeled Agrobacterium tumefaciens DNA are not influenced by addition of 10 4 -fold excess of crown gall tumor DNA. Reconstruction experiments demonstrated that 0.01% added bacterial DNA produces a detectable increase in rate of renaturation of labeled DNA. Crown gall tumor DNA therefore cannot contain as much as 0.01% A. tumefaciens DNA (one entire bacterial genome per three diploid tumor cells). By the same technique, PS8 bacteriophage DNA is not detected in crown gall tumor DNA under conditions that allow detection of 0.0007-0.001% added phage DNA. Crown gall tumor DNA cannot contain as much as one entire phage genome per diploid tumor cell. The presence of a small fraction of either genome (less than 5%), even if present as multiple copies, would escape detection by this method.

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Metadata

Authors
Chilton, M.-D., Currier, T. C., Farrand, S. K., Bendich, A. J., Gordon, M. P., & Nester, E. W.
Venue
Proceedings of the National Academy of Sciences
Published
1974-09
Volume
71
Issue
9
Pages
3672-3676
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2057427118
Cited by
663
References
1
FWCI
16.65
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Agrobacterium tumefaciens DNA and PS8 Bacteriophage DNA Not Detected in Crown Gall Tumors. https://app.cochat.ai/papers/10.1073/pnas.71.9.3672
The paper
Chilton, M.-D., Currier, T. C., Farrand, S. K., Bendich, A. J., Gordon, M. P., & Nester, E. W. (1974). Agrobacterium tumefaciens DNA and PS8 Bacteriophage DNA Not Detected in Crown Gall Tumors. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.71.9.3672

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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