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Investigation of phase transitions of lipids and lipid mixtures by sensitivity differential scanning calorimetry.
Open accessAbstract
High sensitivity differential scanning calorimetry is applied to the study of the thermotropic behavior of mixtures of synthetic phospholipids in multilamellar aqueous suspensions. The systems dimyristoylphosphatidylcholine dipalmitoylphosphatidylcholine, and dimyristoylphosphatidylethanolamine-distearoylphosphatidylcholine, although definitely nonideal, exhibit essentially complete miscibility in both gel and liquid crystalline states, while the system dilauroylphosphatidylcholine-distearoylphosphatidylcholine is monotectic with lateral phase separation in the gel state. Comparison of the observed transition curves with theoretical curves calculated from the calorimetrically determined phase diagrams supports a literal interpretation of the phase diagrams.
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Cited by
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Metadata
- Authors
- Mabrey, S., & Sturtevant, J. M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1976-11
- Volume
- 73
- Issue
- 11
- Pages
- 3862-3866
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2064546283
- Cited by
- 955
- References
- 0
- FWCI
- 9.89
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Investigation of phase transitions of lipids and lipid mixtures by sensitivity differential scanning calorimetry. https://app.cochat.ai/papers/10.1073/pnas.73.11.3862
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- Mabrey, S., & Sturtevant, J. M. (1976). Investigation of phase transitions of lipids and lipid mixtures by sensitivity differential scanning calorimetry. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.73.11.3862
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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