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Cited by 496

The DOI matches its Crossref record.

Asymmetric budding of viruses in epithelial monlayers: a model system for study of epithelial polarity.

Open access
Boulan, E R, Sabatini, D D·1978·Proceedings of the National Academy of Sciences
DOI 10.1073/pnas.75.10.5071
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Abstract

Infection of two different lines of polarized epithelial cells grown as monolayers with several types of enveloped viruses results, for each virus type, in a characteristic asymmetric budding of virions. Influenza virus (WSN strain), simian virus 5, and Sendai virus bud exclusively from the free (apical) surface of the cells, while vesicular stomatitis virus acquires its envelope only from the basolateral plasma membrane. Because different viruses select specific domains of plasma membrane in the same cell type, virus-infected epithelial monolayers can provide an excellent model system for studies of the mechanisms that generate regional differences in the distribution of plasma membrane components of epithelial cells.

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Metadata

Authors
Boulan, E. R., & Sabatini, D. D.
Venue
Proceedings of the National Academy of Sciences
Publisher
Proceedings of the National Academy of Sciences
Published
1978-10
Volume
75
Issue
10
Pages
5071-5075
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
DOI
10.1073/pnas.75.10.5071
OpenAlex
W2156681554
Cited by
496
References
0
FWCI
5.49
Type
journal article
Language
en
Open access
bronze

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.