The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Amyloid fibril protein related to prealbumin in familial amyloidotic polyneuropathy.
Open accessAbstract
Amyloid fibrils were concentrated from the kidney, thyroid, and peripheral nerve of six patients with familial amyloidotic polyneuropathy (FAP). The fibril concentrates were solubilized in 6 M guanidine.HCl and fractionated on Sephadex G-100 columns. The elution profile of all FAP amyloid fibril concentrates revealed a protein of apparent Mr of 14,000, designated the FAP protein, that was absent from normal human tissues treated by the same procedure and from fibrils of a primary amyloidosis liver. Antisera against whole denatured fibril concentrates prepared in rabbits reacted with the FAP protein and a component in normal human serum corresponding to prealbumin. It was further established that the FAP protein shared common antigenic determinants with human prealbumin by its reaction of identity with normal prealbumin using commercial antisera against human prealbumin. Amyloid AL or AA proteins could not be identified in FAP fibrils by sensitive immunochemical assay methods. These results suggest that the FAP protein is a unique and significant component of the FAP amyloid fibrils and that it is closely related to the 13,745 Mr prealbumin subunit.
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Cites
Retinol-binding protein: the transport protein for vitamin A in human plasma
Kanai, M., Raz, A., & Goodman, D. S. (1968) · Journal of Clinical Investigation · doi:10.1172/jci105889 · Cited by 899
Cited by
Westermark, P., Wernstedt, C., Wilander, E., Hayden, D. W., O'Brien, T. D., & Johnson, K. H. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.11.3881 · Cited by 976
Neuritic plaques and cerebrovascular amyloid in Alzheimer disease are antigenically related.
Wong, C. W., Quaranta, V, & Glenner, G. G. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.24.8729 · Cited by 438
Preclinical evaluation of RNAi as a treatment for transthyretin-mediated amyloidosis
Butler, J. S., Chan, A., Costelha, S., Fishman, S., Willoughby, J. L. S., Borland, T. D., Milstein, S., Foster, D. J., Gonçalves, P., Chen, Q., et al. (2016) · Amyloid · doi:10.3109/13506129.2016.1160882 · Cited by 113
Lim, A., Prokaeva, T., McComb, M. E., O'Connor, P. B., Théberge, R., Connors, L. H., Skinner, M., & Costello, C. E. (2002) · Analytical Chemistry · doi:10.1021/ac010780+ · Cited by 63
Cutaneous manifestations of familial amyloidotic polyneuropathy
Rocha, N., Velho, G., Horta, M., Martins, A., & Massa, A. (2005) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2005.01222.x · Cited by 32
Metadata
- Authors
- Costa, P. P., Figueira, A. S., & Bravo, F. R.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1978-09
- Volume
- 75
- Issue
- 9
- Pages
- 4499-4503
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1971309987
- Cited by
- 427
- References
- 1
- FWCI
- 3.76
- Type
- journal article
- Language
- en
- Open access
- green
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- Costa, P. P., Figueira, A. S., & Bravo, F. R. (1978). Amyloid fibril protein related to prealbumin in familial amyloidotic polyneuropathy. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.75.9.4499
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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