The DOI matches its Crossref record.
Cloning of the active thymidine kinase gene of herpes simplex virus type 1 in Escherichia coli K-12.
Open accessAbstract
A herpes simplex virus DNA fragment that is produced by digestion with BamHI endonuclease and carries the thymidine kinase (TK; ATP:thymidine 5'-phosphotransferase, EC 2.7.1.21) gene has been cloned in Escherichia coli. A recombinat plasmid, pFG5, has been analyzed extensively and a detailed restriction map is presented. pFG5 DNA efficiently transforms TK- mouse L cells. The TK coding sequence in the cloned fragment has been localized and a smaller recombinant plasmid, pAG0, also carrying an active TK gene, has been constructed to serve as a more convenient vector for transfer, into TK- cells, of genes previously cloned in E. coli.
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Cited by
Interferon response element of the human gene 6-16.
Porter, A. C., Chernajovsky, Y., Dale, T. C., Gilbert, C. S., Stark, G. R., & Kerr, I. M. (1988) · The EMBO Journal · doi:10.1002/j.1460-2075.1988.tb02786.x · Cited by 274
Mocarski, E. S., Post, L. E., & Roizman, B. (1980) · Cell · doi:10.1016/0092-8674(80)90172-5 · Cited by 186
Donehower, L. A., & Varmus, H. E. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.20.6461 · Cited by 183
Iwasaki, K., & Temin, H. M. (1990) · Genes & Development · doi:10.1101/gad.4.12b.2299 · Cited by 44
Metadata
- Authors
- Colbere-Garapin, F., Chousterman, S., Horodniceanu, F., Kourilsky, P., & Garapin, A. C.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1979-08
- Volume
- 76
- Issue
- 8
- Pages
- 3755-3759
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1984414187
- Cited by
- 230
- References
- 0
- FWCI
- 37.00
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Cloning of the active thymidine kinase gene of herpes simplex virus type 1 in Escherichia coli K-12. https://app.cochat.ai/papers/10.1073/pnas.76.8.3755
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- Colbere-Garapin, F., Chousterman, S., Horodniceanu, F., Kourilsky, P., & Garapin, A. C. (1979). Cloning of the active thymidine kinase gene of herpes simplex virus type 1 in Escherichia coli K-12. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.76.8.3755
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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