The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Heterogeneity of apolipoprotein B: isolation of a new species from human chylomicrons.
Open accessAbstract
Low density lipoproteins and the triglyceride-rich lipoproteins of human serum each contain proteins of high molecular weight termed apolipoprotein B, which have previously been thought to be identical. We have isolated four species of apolipoprotein B with unique molecular weights and amino acid compositions. We have assigned numerical designations to these species in a centile system based upon their relative apparent Mr in NaDodSO4. One which we term B-100, with an apparent Mr of 549,000 +/- 7650 (SD) determined by NaDodSO4 gel electrophoresis, predominates in low density and very low density lipoproteins and is also present in chylomicrons from thoracic duct lymph or from plasma. Substantial amounts of two large proteins designated B-74 (apparent Mr 407,000 +/- 5790) and B-26 (apparent Mr 144,500 +/- 8970), which appear to be complementary fragments or constituents of the B-100 protein, are found in the low density lipoproteins of many individuals. A distinct protein, B-48, with an apparent Mr of 264,000 +/- 8150 is a major and constant constituent of chylomicrons from thoracic duct lymph or from plasma.
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Citations
Cites
Innerarity, T. L., & Mahley, R. W. (1978) · Biochemistry · doi:10.1021/bi00601a013 · Cited by 433
Cited by
Plasma lipoproteins: apolipoprotein structure and function.
Mahley, R. W., Innerarity, T. L., Rall, S. C., & Weisgraber, K. H. (1984) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)34443-6 · Cited by 1,155
Regulation of Plasma Cholesterol by Lipoprotein Receptors
Brown, M. S., Kovanen, P. T., & Goldstein, J. L. (1981) · Science · doi:10.1126/science.6261329 · Cited by 702
The role of lipoproteins in steroidogenesis and cholesterol metabolism in steroidogenic glands
GWYNNE, J. T., & STRAUSS, J. F. (1982) · Endocrine Reviews · doi:10.1210/edrv-3-3-299 · Cited by 586
Patsch, J. R., Karlin, J. B., Scott, L. W., Smith, L. C., & Gotto, A. M. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.5.1449 · Cited by 386
Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation.
Linton, M. F., Gish, R., Hubl, S. T., Bütler, E., Esquivel, C., Bry, W. I., Boyles, J. K., Wardell, M. R., & Young, S. G. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115288 · Cited by 367
Metadata
- Authors
- Kane, J. P., Hardman, D. A., & Paulus, H. E.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1980-05
- Volume
- 77
- Issue
- 5
- Pages
- 2465-2469
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2002892589
- Cited by
- 584
- References
- 1
- FWCI
- 33.92
- Type
- journal article
- Language
- en
- Open access
- green
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- Kane, J. P., Hardman, D. A., & Paulus, H. E. (1980). Heterogeneity of apolipoprotein B: isolation of a new species from human chylomicrons. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.77.5.2465
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