The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Polymorphism in mitochondrial DNA of humans as revealed by restriction endonuclease analysis.
Open accessAbstract
Mitochondrial DNA samples from each of 21 humans of diverse racial and geographic origin were digested with each of 18 restriction endonucleases. The sizes of the resulting DNA fragments were compared after gel electrophoresis. No differences among the samples were detected in digest with 7 of the enzymes. Analysis of digests with the remaining enzymes showed one or more differences. Each of the 21 samples could be characterized individually on the basis of these digests. All between-sample differences could be explained by single base substitutions. No evidence for sequence rearrangements (inversions, transpositions) was obtained. Fourteen of the site alterations were shared by two or more samples; six of these were shared between races. The data indicate that individuals differ from a postulated ancestral mtDNA sequence at 0.18% of their base pairs. On the basis of an estimated rate for base substitution of 1% per 10(6) years [Brown, W. M., George, M., Jr. & Wilson, A. C. (1979) Proc. Natl. Acad. Sci. USA 76, 1967-1971], Homo sapiens could have speciated or passed through a severe population constriction as recently as 180,000 years ago. The data suggest that group-specific patterns of cleavage exist. The high resolution and precision afforded by this method of analysis makes possible the investigation of many questions concerning human population genetics, evolution, and recent history.
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Citations
Cites
Mathematical model for studying genetic variation in terms of restriction endonucleases.
Nei, M., & Li, W. H. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.10.5269 · Cited by 10,402
Rapid evolution of animal mitochondrial DNA
Brown, W. M., George, M., & Wilson, A. C. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.4.1967 · Cited by 3,439
Self-citationManiatis, T., Jeffrey, A., & Van deSande, H. (1975) · Biochemistry · doi:10.1021/bi00688a010 · Cited by 1,121
Studies on the cleavage of bacteriophage lambda DNA with EcoRI restriction endonuclease
Thomas, M., & Davis, R. W. (1975) · Journal of Molecular Biology · doi:10.1016/0022-2836(75)90383-6 · Cited by 795
The nucleotide sequence of bacteriophage φX174
Sanger, F., Coulson, A. R., Friedmann, T., Air, G. M., Barrell, B. G., Brown, N. L., Fiddes, J. C., Hutchison, C. A., Slocombe, P. M., & Smith, M. (1978) · Journal of Molecular Biology · doi:10.1016/0022-2836(78)90346-7 · Cited by 693
Phosphorylation of nucleic acid by an enzyme from T4 bacteriophage-infected Escherichia coli.
Richardson, C. C. (1965) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.54.1.158 · Cited by 607
A different genetic code in human mitochondria
Barrell, B. G., Bankier, A. T., & Drouin, J. (1979) · Nature · doi:10.1038/282189a0 · Cited by 571
Use of restriction enzymes to study eukaryotic DNA methylation
Bird, A. P., & Southern, E. M. (1978) · Journal of Molecular Biology · doi:10.1016/0022-2836(78)90242-5 · Cited by 443
Swanstrom, R., & Shank, P. R. (1978) · Analytical Biochemistry · doi:10.1016/0003-2697(78)90333-0 · Cited by 415
Estimation of DNA sequence divergence from comparison of restriction endonuclease digests
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Cited by
Mitochondrial DNA and human evolution
Cann, R. L., Stoneking, M., & Wilson, A. C. (1987) · Nature · doi:10.1038/325031a0 · Cited by 3,100
Mitochondrial DNA sequences of primates: tempo and mode of evolution
Brown, W. M., Prager, E. M., Wang, A., & Wilson, A. C. (1982) · Journal of Molecular Evolution · doi:10.1007/bf01734101 · Cited by 1,554
Self-citationMaternal inheritance of human mitochondrial DNA.
Giles, R. E., Blanc, H., Cann, H. M., & Wallace, D. C. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.11.6715 · Cited by 1,365
Torroni, A., Schurr, T. G., Yang, C. C., Szathmary, E. J., Williams, R. C., Schanfield, M. S., Troup, G. A., Knowler, W. C., Lawrence, D. N., & Weiss, K. M. (1992) · Genetics · doi:10.1093/genetics/130.1.153 · Cited by 498
Mitochondrial DNA and the evolutionary genetics of higher animals
Avise, J. C. (1986) · Philosophical Transactions of the Royal Society of London. B, Biological Sciences · doi:10.1098/rstb.1986.0011 · Cited by 465
Metadata
- Authors
- Brown, W. M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1980-06
- Volume
- 77
- Issue
- 6
- Pages
- 3605-3609
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1982456351
- Cited by
- 465
- References
- 24
- FWCI
- 15.37
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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