The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Monitoring fibroblast behavior in tissue culture with an applied electric field.
Open accessAbstract
Mammalian fibroblasts have been cultured on evaporated gold electrodes subjected to an alternating electric field at 4000 Hz. The system consists of a large (approximately equal to 2 cm2) and a small (approximately equal to 3 X 10(-4) cm2) electrode bathed in tissue culture medium. The applied electric field produces a voltage drop at the boundary between the solution and the small electrode of a few mV at a current density of a few mA/cm2. The small population of cells that attach and spread on this electrode have a marked effect on the measured impedance and also cause it to fluctuate with time. The amplitude of these fluctuations is greatly reduced by cytochalasin B (10 microM), suggesting they are a consequence of cell movement.
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Cites
Polarized monolayers formed by epithelial cells on a permeable and translucent support
Cereijido, M., Robbins, E., Dolan, W., Rotunno, C., & Sabatini, D. (1978) · The Journal of cell biology · doi:10.1083/jcb.77.3.853 · Cited by 868
Mechanism of action of cytochalasin B on actin
MacLean-Fletcher, S. (1980) · Cell · doi:10.1016/0092-8674(80)90619-4 · Cited by 755
A miniature microelectrode array to monitor the bioelectric activity of cultured cells
THOMASJR, C., SPRINGER, P., LOEB, G., BERWALDNETTER, Y., & OKUN, L. (1972) · Experimental Cell Research · doi:10.1016/0014-4827(72)90481-8 · Cited by 580
Transepithelial transport in cell culture.
Misfeldt, D. S., Hamamoto, S. T., & Pitelka, D. R. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.4.1212 · Cited by 502
Cited by
Conducting polymers in biomedical engineering
Guimard, N. K., Gomez, N., & Schmidt, C. E. (2007) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2007.05.012 · Cited by 1,599
Denning, C., Borgdorff, V., Crutchley, J., Firth, K. S. A., George, V., Kalra, S., Kondrashov, A., Hoang, M. D., Mosqueira, D., Patel, A., et al. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.10.014 · Cited by 293
“These characteristics are exploited by electric cell-substrate impedance sensing platforms, which incorporate gold-film electrodes into the bottom of tissue-culture plates [201,202].”
BackgroundNguyen, T. A., Yin, T.-I., Reyes, D., & Urban, G. A. (2013) · Analytical Chemistry · doi:10.1021/ac402761s · Cited by 189
The effect of aging in primary human dermal fibroblasts
Lago, J. C., & Puzzi, M. B. (2019) · PLOS ONE · doi:10.1371/journal.pone.0219165 · Cited by 168
Wu, S., Liu, X., Zhou, X., Liang, X. M., Gao, D., Liu, H., Zhao, G., Zhang, Q., & Wu, X. (2016) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2015.09.024 · Cited by 64
Metadata
- Authors
- Giaever, I., & Keese, C. R.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1984-06
- Volume
- 81
- Issue
- 12
- Pages
- 3761-3764
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2036464893
- Cited by
- 608
- References
- 4
- FWCI
- 0.37
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
