The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Evidence for active synapse formation or altered postsynaptic metabolism in visual cortex of rats reared in complex environments.
Open accessAbstract
Animals placed in complex environments develop greater numbers of visual cortex synapses per neuron than animals housed in standard cages. Increased numbers of synapses could theoretically arise from (i) active formation of new synapses, or (ii) selective stabilization of constitutively produced synapses. The postsynaptic location of polyribosomal aggregates appears to be an indicator of newly forming synapses. In developmental synaptogenesis and adult reactive (to injury) synaptogenesis, polyribosomes are more frequently found at spine synapses and are more likely to appear in the spine head and stem. In the visual cortex of rats from complex environments, there was a greater frequency of spine synapses associated with polyribosomes, relative to rats from individual or group cages. Furthermore, a greater percentage of these spines had polyribosomes in the head and stem region. This suggests that synapses in this region may be actively induced by neural activity arising from the complex environment experience.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Acetylcholine Receptor: An Allosteric Protein
Changeux, J.-P., Devillers-Thiéry, A., & Chemouilli, P. (1984) · Science · doi:10.1126/science.6382611 · Cited by 623
Rearing complexity affects branching of dendrites in the visual cortex of the rat
Volkmar, F. R., & Greenough, W. T. (1972) · Science · doi:10.1126/science.176.4042.1445 · Cited by 513
Self-citationTurner, A. M., & Greenough, W. T. (1985) · Brain Research · doi:10.1016/0006-8993(85)90525-6 · Cited by 459
Self-citationEffects of differential experience on dendritic spine counts in rat cerebral cortex
Globus, A., Rosenzweig, M. R., Bennett, E. L., & Diamond, M. C. (1973) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0033910 · Cited by 436
Rate and extent of recovery from dark rearing in the visual cortex of the mouse
Valverde, F. (1971) · Brain Research · doi:10.1016/0006-8993(71)90302-7 · Cited by 235
Rothblat, L. A., & Schwartz, M. L. (1979) · Brain Research · doi:10.1016/0006-8993(79)90203-8 · Cited by 103
Cited by
Experience-dependent structural synaptic plasticity in the mammalian brain
Holtmaat, A., & Svoboda, K. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2699 · Cited by 1,934
Enriched environments, experience-dependent plasticity and disorders of the nervous system
Nithianantharajah, J., & Hannan, A. J. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1970 · Cited by 1,771
Experience and brain development
Greenough, W. T., Black, J. E., & Wallace, C. S. (1987) · Child Development · doi:10.2307/1130197 · Cited by 1,398
Self-citationIzquierdo, I., & Medina, J. H. (1997) · Neurobiology of Learning and Memory · doi:10.1006/nlme.1997.3799 · Cited by 959
Tottenham, N., Hare, T. A., Quinn, B. T., McCarry, T. W., Nurse, M., Gilhooly, T., Millner, A., Galvan, A., Davidson, M. C., Eigsti, I., et al. (2010) · Developmental Science · doi:10.1111/j.1467-7687.2009.00852.x · Cited by 905
Metadata
- Authors
- Greenough, W. T., Hwang, H. M., & Gorman, C.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1985-07
- Volume
- 82
- Issue
- 13
- Pages
- 4549-4552
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2024570545
- Cited by
- 195
- References
- 6
- FWCI
- 2.79
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Evidence for active synapse formation or altered postsynaptic metabolism in visual cortex of rats reared in complex environments. https://app.cochat.ai/papers/10.1073/pnas.82.13.4549
- The paper
- Greenough, W. T., Hwang, H. M., & Gorman, C. (1985). Evidence for active synapse formation or altered postsynaptic metabolism in visual cortex of rats reared in complex environments. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.82.13.4549
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
