The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
UGA is read as tryptophan in Mycoplasma capricolum.
Open accessAbstract
UGA is a nonsense or termination (opal) codon throughout prokaryotes and eukaryotes. However, mitochondria use not only UGG but also UGA as a tryptophan codon. Here, we show that UGA also codes for tryptophan in Mycoplasma capricolum, a wall-less bacterium having a genome only 20-25% the size of the Escherichia coli genome. This conclusion is based on the following evidence. First, the nucleotide sequence of the S3 and L16 ribosomal protein genes from M. capricolum includes UGA codons in the reading frames; they appear at positions corresponding to tryptophan in E. coli S3 and L16. Second, a tRNATrp gene and its product tRNA found in M. capricolum have the anticodon sequence 5' U-C-A 3', which can form a complementary base-pairing interaction with UGA.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
DNA sequencing with chain-terminating inhibitors
Sanger, F., Nicklen, S., & Coulson, A. R. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.12.5463 · Cited by 68,572
A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments
Messing, J., & Vieira, J. (1982) · Gene · doi:10.1016/0378-1119(82)90016-6 · Cited by 2,896
Codon—anticodon pairing: The wobble hypothesis
Crick, F. H. C. (1966) · Journal of Molecular Biology · doi:10.1016/s0022-2836(66)80022-0 · Cited by 2,029
Margulis, L. (1981) · Cited by 1,399
Direct chemical method for sequencing RNA.
Peattie, D. A. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.4.1760 · Cited by 940
A different genetic code in human mitochondria
Barrell, B. G., Bankier, A. T., & Drouin, J. (1979) · Nature · doi:10.1038/282189a0 · Cited by 571
Tryptophan transfer RNA as the UGA suppressor
Hirsh, D. (1971) · Journal of Molecular Biology · doi:10.1016/0022-2836(71)90362-7 · Cited by 361
Different pattern of codon recognition by mammalian mitochondrial tRNAs.
Barrell, B. G., Anderson, S., Bankier, A. T., de Bruijn, M. H., Chen, E., Coulson, A. R., Drouin, J., Eperon, I. C., Nierlich, D. P., Roe, B. A., et al. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.6.3164 · Cited by 270
Heckman, J. E., Sarnoff, J., Alzner-DeWeerd, B., Yin, S., & RajBhandary, U. L. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.6.3159 · Cited by 246
Cited by
Insights into the phylogeny and coding potential of microbial dark matter
Rinke, C., Schwientek, P., Sczyrba, A., Ivanova, N. N., Anderson, I. J., Cheng, J.-F., Darling, A., Malfatti, S., Swan, B. K., Gies, E. A., et al. (2013) · Nature · doi:10.1038/nature12352 · Cited by 2,394
A phylogenetic analysis of the mycoplasmas: basis for their classification
Weisburg, W. G., Tully, J. G., Rose, D. L., Petzel, J. P., Oyaizu, H., Yang, D., Mandelco, L., Sechrest, J., Lawrence, T. G., & Van Etten, J. (1989) · Journal of Bacteriology · doi:10.1128/jb.171.12.6455-6467.1989 · Cited by 747
Zinoni, F., Birkmann, A., Stadtman, T. C., & Böck, A. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.13.4650 · Cited by 486
The neutral theory of molecular evolution: A review of recent evidence
KIMURA, M. (1991) · The Japanese Journal of Genetics · doi:10.1266/jjg.66.367 · Cited by 295
The Triplet Code From First Principles
Trifonov, E. N. (2004) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2004.10506975 · Cited by 246
Metadata
- Authors
- Yamao, F., Muto, A., Kawauchi, Y., Iwami, M., Iwagami, S., Azumi, Y., & Osawa, S.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1985-04
- Volume
- 82
- Issue
- 8
- Pages
- 2306-2309
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2058867258
- Cited by
- 305
- References
- 19
- FWCI
- 5.69
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: UGA is read as tryptophan in Mycoplasma capricolum. https://app.cochat.ai/papers/10.1073/pnas.82.8.2306
- The paper
- Yamao, F., Muto, A., Kawauchi, Y., Iwami, M., Iwagami, S., Azumi, Y., & Osawa, S. (1985). UGA is read as tryptophan in Mycoplasma capricolum. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.82.8.2306
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
