The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Human immunodeficiency virus can productively infect cultured human glial cells.
Open accessAbstract
Six isolates of the human immunodeficiency virus (HIV) showed differences in their ability to productively infect glioma-derived cell lines and early-passage human brain cell cultures. Susceptibility to HIV infection correlated well with the expression of the astrocyte marker glial fibrillary acidic protein. The CD4 molecule was expressed on some, but not all, of the brain-derived cells; however, no correlation was observed between CD4 protein expression and susceptibility to virus infection. The results show that HIV can productively infect human brain cells, particularly those of glial origin, and suggest that these cell types in the brain can harbor the virus.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Barré-Sinoussi, F., Chermann, J. C., Rey, F., Nugeyre, M. T., Chamaret, S., Gruest, J., Dauguet, C., Axler-Blin, C., Vézinet-Brun, F., Rouzioux, C., et al. (1983) · Science · doi:10.1126/science.6189183 · Cited by 7,038
Gallo, R. C., Salahuddin, S. Z., Popovic, M., Shearer, G. M., Kaplan, M., Haynes, B. F., Palker, T. J., Redfield, R., Oleske, J., Safai, B., et al. (1984) · Science · doi:10.1126/science.6200936 · Cited by 3,641
The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus
Dalgleish, A. G., Beverley, P. C. L., Clapham, P. R., Crawford, D. H., Greaves, M. F., & Weiss, R. A. (1984) · Nature · doi:10.1038/312763a0 · Cited by 3,533
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV
Klatzmann, D., Champagne, E., Chamaret, S., Gruest, J., Guetard, D., Hercend, T., Gluckman, J.-C., & Montagnier, L. (1984) · Nature · doi:10.1038/312767a0 · Cited by 2,436
Detection of AIDS Virus in Macrophages in Brain Tissue from AIDS Patients with Encephalopathy
Koenig, S., Gendelman, H. E., Orenstein, J. M., Dal Canto, M. C., Pezeshkpour, G. H., Yungbluth, M., Janotta, F., Aksamit, A., Martin, M. A., & Fauci, A. S. (1986) · Science · doi:10.1126/science.3016903 · Cited by 1,698
Isolation of Lymphocytopathic Retroviruses from San Francisco Patients with AIDS
Levy, J. A., Hoffman, A. D., Kramer, S. M., Landis, J. A., Shimabukuro, J. M., & Oshiro, L. S. (1984) · Science · doi:10.1126/science.6206563 · Cited by 1,436
Self-citationWiley, C. A., Schrier, R. D., Nelson, J. A., Lampert, P. W., & Oldstone, M. B. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.18.7089 · Cited by 1,243
An acidic protein isolated from fibrous astrocytes
Eng, L. F., Vanderhaeghen, J. J., Bignami, A., & Gerstl, B. (1971) · Brain Research · doi:10.1016/0006-8993(71)90668-8 · Cited by 1,230
Levy, R. M., Bredesen, D. E., & Rosenblum, M. L. (1985) · Journal of Neurosurgery · doi:10.3171/jns.1985.62.4.0475 · Cited by 1,129
Self-citationHo, D. D., Rota, T. R., Schooley, R. T., Kaplan, J. C., Allan, J. D., Groopman, J. E., Resnick, L., Felsenstein, D., Andrews, C. A., & Hirsch, M. S. (1985) · New England Journal of Medicine · doi:10.1056/nejm198512123132401 · Cited by 1,102
Cited by
The Brain in AIDS: Central Nervous System HIV-1 Infection and AIDS Dementia Complex
Price, R. W., Brew, B., Sidtis, J., Rosenblum, M., Scheck, A. C., & Cleary, P. (1988) · Science · doi:10.1126/science.3277272 · Cited by 1,245
Self-citationNeuropathology of Human Immunodeficiency Virus Infection
Budka, H. (1991) · Brain Pathology · doi:10.1111/j.1750-3639.1991.tb00656.x · Cited by 416
Metadata
- Authors
- Cheng-Mayer, C., Rutka, J. T., Rosenblum, M. L., McHugh, T., Stites, D. P., & Levy, J. A.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1987-05
- Volume
- 84
- Issue
- 10
- Pages
- 3526-3530
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1964350991
- Cited by
- 297
- References
- 26
- FWCI
- 7.29
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Human immunodeficiency virus can productively infect cultured human glial cells. https://app.cochat.ai/papers/10.1073/pnas.84.10.3526
- The paper
- Cheng-Mayer, C., Rutka, J. T., Rosenblum, M. L., McHugh, T., Stites, D. P., & Levy, J. A. (1987). Human immunodeficiency virus can productively infect cultured human glial cells. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.84.10.3526
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
