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Cited by 514

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

A human major histocompatibility complex class I gene that encodes a protein with a shortened cytoplasmic segment.

Open access
Geraghty, D E, Koller, B H, Orr, H T·1987·Proceedings of the National Academy of Sciences

Abstract

We have cloned genomic DNA encoding a non-HLA-A, -B, -C class I gene located within a HindIII-generated restriction fragment of 6.0 kilobase pairs. This gene, designated HLA-6.0, is as homologous to HLA-A and HLA-B as they are to each other. The HLA class I protein encoded by HLA-6.0 is similar in organization to the HLA-A-, -B-, and -C-encoded proteins except that an in-frame termination codon prevents translation of a majority of the cytoplasmic region of the HLA-6.0 polypeptide. Moreover, the promoter region of HLA-6.0 resembles the promoter region of a Qa region gene. These structural features of HLA-6.0 suggest that this non-HLA-A, -B, -C gene is a structural homolog of a murine Qa region class I gene.

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Metadata

Authors
Geraghty, D. E., Koller, B. H., & Orr, H. T.
Venue
Proceedings of the National Academy of Sciences
Published
1987-12
Volume
84
Issue
24
Pages
9145-9149
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2046788012
Cited by
514
References
1
FWCI
5.15
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: A human major histocompatibility complex class I gene that encodes a protein with a shortened cytoplasmic segment. https://app.cochat.ai/papers/10.1073/pnas.84.24.9145
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Geraghty, D. E., Koller, B. H., & Orr, H. T. (1987). A human major histocompatibility complex class I gene that encodes a protein with a shortened cytoplasmic segment. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.84.24.9145

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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