Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains.
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- Neuroprotective Effects and Mechanisms of Senegenin, an Effective Compound Originated From the Roots of Polygala TenuifoliaZhe Chen, Yang Yu, Ying Han, Xijun Wang · 2022 · Frontiers in Pharmacology
- Role of the ubiquitin–proteasome pathway in the diagnosis of human diseasesJakub Gołąb, Thomas M. Bauer, Volker Daniel, Cord Naujokat · 2003 · Clinica Chimica Acta
- Pick's disease immunohistochemistry: new alterations and Alzheimer's disease comparisonsOsamu Yasuhara, Akinori Matsuo, Ikuo Tooyama, Hiroshi Kimurâ, Edith G. McGeer, Patrick L. McGeer · 1995 · Acta Neuropathologica
- Ubiquitin and heat shock protein expression in amyotrophic lateral sclerosisO. Garofalo, Peter G. E. Kennedy, Michael Swash, Joanne E. Martin, Philip J. Luthert, Brian H. Anderton, P. Nigel Leigh · 1991 · Neuropathology and Applied Neurobiology
- Proteasome or calpain inhibition does not alter cellular tau levels in neuroblastoma cells or primary neuronsMaile R. Brown, Vimala Bondada, Jeffrey N. Keller, Jeffery A. Thorpe, James W. Geddes · 2005 · Journal of Alzheimer s Disease
- Evidence for a particulate location of ubiquitin conjugates and ubiquitin-conjugating enzymes in rabbit brain.Mauro Magnani, Giordano Serafini, A. Antonelli, Manuela Malatesta, Giancarlo Gazzanelli · 1991 · Journal of Biological Chemistry
- Immunoreactivity to ubiquitin—protein conjugates is present early in the disease process in the brains of scrapie‐infected miceJames S Lowe, Jill Fergusson, Nigel Kenward, Lajos László, Michael Landon, Christine F. Farquhar, John Brown, James Hope, R. John Mayer · 1992 · The Journal of Pathology
- Neuronal degeneration in human diseases and animal modelsDonald L. Price, Lee J. Martin, Richard E. Clatterbuck, Vassilis E. Koliatsos, Sangram S. Sisodia, Lary C. Walker, Linda C. Cork · 1992 · Journal of Neurobiology
- Immunization targeting a minor plaque constituent clears β-amyloid and rescues behavioral deficits in an Alzheimer's disease mouse modelJosé Morales‐Corraliza, Stephen D. Schmidt, Matthew J. Mazzella, Jason D. Berger, Donald A. Wilson, Daniel W. Wesson, Mathias Jucker, Efrat Levy, Ralph A. Nixon, Paul M. Mathews · 2012 · Neurobiology of Aging
- Ubiquitin is Associated with Early Truncation of Tau Protein at Aspartic Acid421 during the Maturation of Neurofibrillary Tangles in Alzheimer's DiseaseFrancisco García‐Sierra, José Jaime Jarero-Basulto, Zdena Krištofíková, Emerich Majer, Lester I. Binder, Daniela Řı́pová · 2011 · Brain Pathology
- Immunohistochemical study of constituents other than β-protein in canine senile plaques and cerebral amyloid angiopathyKazuyuki Uchida, Koji Kuroki, Tomoko Yoshino, Ryoji Yamaguchi, Susumu TATEYAMA · 1997 · Acta Neuropathologica
- The neuronal ubiquitin-proteasome system: Murine models and their neurological phenotypePaula van Tijn, Elly M. Hol, Fred W. van Leeuwen, David F. Fischer · 2008 · Progress in Neurobiology
- The Amyloid Peptide and Its Precursor in Alzheimer's DiseaseJean Noël Octave · 1995 · Reviews in the Neurosciences
- Diagnosis of Alzheimer's DiseaseBarry Reisberg, Alistair S. Burns, Henry Brodaty, Robin Eastwood, Martin N. Rossor, Norman Sartorius, Bengt G. Winblad · 1997 · International Psychogeriatrics
- Ubiquitin and the Molecular Pathology of Neurodegenerative DiseasesJames S Lowe, John Mayer, Michael Landon, Robert Layfield · 2001 · Advances in experimental medicine and biology
- Synphilin-1 isoforms in Parkinson’s disease: regulation by phosphorylation and ubiquitylationRaymonde Szargel, R. Rott, Simone Engelender · 2007 · Cellular and Molecular Life Sciences
- Biomarkers for Alzheimer Disease in Cerebrospinal Fluid, Urine, and BloodAnders Lönneborg · 2008 · Molecular Diagnosis & Therapy
- Two distinct ubiquitin immunoreactive senile plaques in Alzheimer's disease: relationship with the intellectual status in 29 casesY. He, Pia Delaère, Charles J. Duyckaerts, Marcin Wąsowicz, F. Piette, Jean‐Jacques Hauw · 1993 · Acta Neuropathologica
- Current biomarkers and treatment strategies in Alzheimer disease: An overview and future perspectivesRitesh P. Bhole, Rupesh V. Chikhale, Karishma Manohar Rathi · 2023 · IBRO Neuroscience Reports
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- Abortive oncogeny and cell cycle-mediated events in Alzheimer diseaseArun K. Raina, Xiongwei Zhu, Mervyn J. Monteiro, Atsushi Takeda, Mark A. Smith · 2000 · Springer eBooks
- Alzheimer neurofibrillary tangles contain 2.1 nm filaments structurally identical to the microtubule-associated protein τ: a high-resolution transmission electron microscope study of tangles and senile plaque core amyloidGeorge C. Ruben, Khalid Iqbal, Henryk M. Wisniewski, John Emil Johnson, Inge Grundke · 1992 · Brain Research
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- Chapter 3 Ubiquitin and its role in neurodegenerationJane Arnold, Simon P. Dawson, Jill Fergusson, Michael Landon, R. John Mayer, James S Lowe · 1998 · Progress in brain research
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- TMP21 degradation is mediated by the ubiquitin‐proteasome pathwayShengchun Liu, Kelley Bromley‐Brits, Kun Xia, Jill Mittelholtz, Ruitao Wang, Weihong Song · 2008 · European Journal of Neuroscience
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- Post-Translational Modifications in Tau and Their Roles in Alzheimer's PathologySubha Kalyaanamoorthy, Stanley K. A. Opare, Xiaoxiao Xu, Aravindhan Ganesan, Praveen P. N. Rao · 2024 · Current Alzheimer Research
- Proteasome subunit proteins and neuropathology in tauopathies and synucleinopathies: Consequences for proteomic analysesMohamed Zouambia, David F. Fischer, Barbara Hobo, Rob A. I. de Vos, Elly M. Hol, Ian M. Varndell, Paul W. Sheppard, Fred W. van Leeuwen · 2008 · PROTEOMICS
- Ubiquitin and β-amyloid-protein in inclusion body myositis (IBM), familial IBM-like disorder and oculopharyngeal muscular dystrophy: An immunocytochemical studyAnne Helbling-Leclerc, Fernando M. S. Tomé, Michel Fardeau · 1993 · Neuromuscular Disorders
- Non-covalent interaction of ubiquitin with insulin-degrading enzymeTomo Šarić, Dieter Müller, Hans-Joachim Seitz, Krešimir Pavelić · 2003 · Molecular and Cellular Endocrinology
- Exploring the anti-ferroptosis mechanism of Kai-Xin-San against Alzheimer's disease through integrating network pharmacology, bioinformatics, and experimental validation strategy in vivo and in vitroChenchen Yan, Song Yang, Simai Shao, Runru Zu, Lu Hao, Yuanzhao Chen, Yangang Zhou, Xiran Ying, Shixie Xiang, Peixu Zhang et al. · 2024 · Journal of Ethnopharmacology
- Evidence Linking Protein Misfolding to Quality Control in Progressive Neurodegenerative DiseasesMd. Tanvir Kabir, Md. Sahab Uddin, Ahmed Abdeen, Ghulam Md Ashraf, Asma Perveen, Abdul Hafeez, May Nasser Bin-Jumah, Mohamed M. Abdel‐Daim · 2020 · Current Topics in Medicinal Chemistry
- Increased ubiquitin immunoreactivity in hepatocellular carcinomas and precancerous lesions of the liverTakuya Osada, Michiie Sakamoto, Hideki Nishibori, Keiichi Iwaya, Yoshihiro Matsuno, Tetsuichiro Muto, Setsuo Hirohashi · 1997 · Journal of Hepatology
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- Methods for the purification of ubiquitinated ProteinsEmma Tomlinson, Naaventhan Palaniyappan, David Tooth, Robert Layfield · 2007 · PROTEOMICS
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- Alzheimer's Disease and the “Valley of Death”: Not Enough Guidance from Human Brain Tissue?Thomas G. Beach · 2012 · Journal of Alzheimer s Disease
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