The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility.
Open accessAbstract
Analysis of sequence variation in the polymorphic second exon of the major histocompatibility complex genes HLA-DQ alpha and -DQ beta has revealed 8 allelic variants at the alpha locus and 13 variants at the beta locus. Correlation of sequence variation with serologic typing suggests that the DQw2, DQw3, and DQ(blank) types are determined by the DQ beta subunit, while the DQw1 specificity is determined by DQ alpha. The nature of the amino acid at position 57 in the DQ beta subunit is correlated with susceptibility to insulin-dependent diabetes mellitus. This region of the DQ beta chain contains shared peptides with Epstein-Barr virus and rubella virus.
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Cites
Saiki, R. K., Scharf, S., Faloona, F., Mullis, K. B., Horn, G. T., Erlich, H. A., & Arnheim, N. (1985) · Science · doi:10.1126/science.2999980 · Cited by 8,956
Self-citationEisenbarth (1986) · doi:10.1056/nejm198605223142106 · Cited by 1,659
Cited by
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
Brown, J. H., Jardetzky, T. S., Gorga, J. C., Stern, L. J., Urban, R. G., Strominger, J. L., & Wiley, D. C. (1993) · Nature · doi:10.1038/364033a0 · Cited by 2,379
HLA DR-DQ Haplotypes and Genotypes and Type 1 Diabetes Risk
Erlich, H., Valdes, A. M., Noble, J., Carlson, J. A., Varney, M., Concannon, P., Mychaleckyj, J. C., Todd, J. A., Bonella, P., Fear, A. L., et al. (2008) · Diabetes · doi:10.2337/db07-1331 · Cited by 790
Self-citationHLA class II‐associated genetic susceptibility in multiple sclerosis: A critical evaluation
Olerup, O., & Hillert, J. (1991) · Tissue Antigens · doi:10.1111/j.1399-0039.1991.tb02029.x · Cited by 490
Rewers, M., Bugawan, T. L., Norris, J. M., Blair, A., Beaty, B., Hoffman, M., McDuffie, R. S., Hamman, R. F., Klingensmith, G., Eisenbarth, G. S., et al. (1996) · Diabetologia · doi:10.1007/s001250050514 · Cited by 422
Self-citationNoble, J. A., & Erlich, H. A. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a007732 · Cited by 335
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Metadata
- Authors
- Horn, G. T., Bugawan, T. L., Long, C. M., & Erlich, H. A.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1988-08
- Volume
- 85
- Issue
- 16
- Pages
- 6012-6016
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2001412093
- Cited by
- 377
- References
- 2
- FWCI
- 34.93
- Type
- journal article
- Language
- en
- Open access
- green
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- Horn, G. T., Bugawan, T. L., Long, C. M., & Erlich, H. A. (1988). Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.85.16.6012
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