The DOI matches its Crossref record.
Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor.
Open accessAbstract
The cDNA for the Syrian hamster alpha 1-adrenergic receptor has been cloned with oligonucleotides corresponding to the partial amino acid sequence of the receptor protein purified from DDT1MF-2 smooth muscle cells. The deduced amino acid sequence encodes a 515-residue polypeptide that shows the most sequence identity with the other adrenergic receptors and the putative protein product of the related clone G-21. Similarities with the muscarinic cholinergic receptors are also evident. Expression studies in COS-7 cells confirm that we have cloned the alpha 1-adrenergic receptor that couples to inositol phospholipid metabolism.
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Metadata
- Authors
- Cotecchia, S., Schwinn, D. A., Randall, R. R., Lefkowitz, R. J., Caron, M. G., & Kobilka, B. K.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1988-10
- Volume
- 85
- Issue
- 19
- Pages
- 7159-7163
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2033653650
- Cited by
- 562
- References
- 0
- FWCI
- 12.32
- Type
- journal article
- Language
- en
- Open access
- green
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- Cotecchia, S., Schwinn, D. A., Randall, R. R., Lefkowitz, R. J., Caron, M. G., & Kobilka, B. K. (1988). Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.85.19.7159
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