The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Molecular cloning of cDNA encoding a second cellular retinoic acid-binding protein.
Open accessAbstract
The vitamin A derivative retinoic acid is known to be a potent agent for control of differentiation and proliferation of epithelial cells and to exert profound effects on pattern formation during embryogenesis. Its action at the molecular level appears to be mediated by two distinct classes of proteins: a family of nuclear receptors that regulates gene transcription in a ligand-dependent fashion and a small cellular retinoic acid-binding protein (CRABP) for which a precise function remains to be elucidated. In this report, we describe the identification (by molecular cloning of its cDNA) of an isoform of CRABP, referred to as CRABP-II, expressed at high levels during mouse embryogenesis and in adult skin. We also show that CRABP-II mRNA levels are induced by at least 50-fold upon treatment of F9 teratocarcinoma cells with retinoic acid. The up-regulation of the gene encoding CRABP-II by its ligand suggests that CRABP-II might be involved in a feedback regulatory role in the mechanism of action of retinoic acid on cellular differentiation.
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Cites
A human retinoic acid receptor which belongs to the family of nuclear receptors
Petkovich, M., Brand, N. J., Krust, A., & Chambon, P. (1987) · Nature · doi:10.1038/330444a0 · Cited by 2,214
Identification of a receptor for the morphogen retinoic acid
Giguere, V., Ong, E. S., Segui, P., & Evans, R. M. (1987) · Nature · doi:10.1038/330624a0 · Cited by 1,965
Lammer, E. J., Chen, D. T., Hoar, R. M., Agnish, N. D., Benke, P. J., Braun, J. T., Curry, C. J., Fernhoff, P. M., Grix, A. W., Lott, I. T., et al. (1985) · New England Journal of Medicine · doi:10.1056/nejm198510033131401 · Cited by 1,942
Cited by
Rossant, J., Zirngibl, R., Cado, D., Shago, M., & Giguère, V (1991) · Genes & Development · doi:10.1101/gad.5.8.1333 · Cited by 732
Self-citationMangelsdorf, D. J., Umesono, K., Kliewer, S. A., Borgmeyer, U., Ong, E. S., & Evans, R. M. (1991) · Cell · doi:10.1016/0092-8674(81)90018-0 · Cited by 647
Smith, M. A., Parkinson, D. R., Cheson, B. D., & Friedman, M. A. (1992) · Journal of Clinical Oncology · doi:10.1200/jco.1992.10.5.839 · Cited by 486
Lipid-Binding Proteins: A Family of Fatty Acid and Retinoid Transport Proteins
Banaszak, L., Winter, N., Xu, Z., Bernlohr, D. A., Cowan, S., & Jones, A. T. (1994) · Advances in Protein Chemistry · doi:10.1016/s0065-3233(08)60639-7 · Cited by 485
Retinoid-binding proteins: mediators of retinoid action
NOY, N. (2000) · Biochemical Journal · doi:10.1042/bj3480481 · Cited by 422
Metadata
- Authors
- Giguère, V, Lyn, S., Yip, P., Siu, C. H., & Amin, S.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1990-08
- Volume
- 87
- Issue
- 16
- Pages
- 6233-6237
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1982478041
- Cited by
- 209
- References
- 3
- FWCI
- 9.99
- Type
- journal article
- Language
- en
- Open access
- green
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- Giguère, V, Lyn, S., Yip, P., Siu, C. H., & Amin, S. (1990). Molecular cloning of cDNA encoding a second cellular retinoic acid-binding protein. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.87.16.6233
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