The DOI matches its Crossref record.
Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.
Open accessAbstract
The nucleotide sequence of the Japanese type of hepatitis C virus (HCV-J) genome, consisting of 9413 nucleotides, was determined by analyses of cDNA clones from plasma specimens from Japanese patients with chronic hepatitis. HCV-J genome contains a long open reading frame that can encode a sequence of 3010 amino acid residues. Comparison of HCV-J with the American isolate of HCV showed 22.6% difference in nucleotide sequence and 15.1% difference in amino acid sequence. Thus HCV-J and the American isolate of HCV are probably different subtypes of HCV. The relationship of HCV-J with other animal RNA virus families and the putative organization of the HCV-J genome are discussed.
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Cited by
Miyake, S., Makimura, M., Kanegae, Y., Harada, S., Sato, Y., Takamori, K., Tokuda, C., & Saito, I. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.3.1320 · Cited by 788
Yoshioka, K., Kakumu, S., Wakita, T., Ishikawa, T., Itoh, Y., Takayanagi, M., Higashi, Y., Shibata, M., & Morishima, T. (1992) · Hepatology · doi:10.1002/hep.1840160203 · Cited by 668
Wang, C., Sarnow, P., & Siddiqui, A. (1993) · Journal of Virology · doi:10.1128/jvi.67.6.3338-3344.1993 · Cited by 441
Patient-to-Patient Transmission of Hepatitis C Virus during Colonoscopy
Bronowicki, J.-P., Venard, V., Botté, C., Monhoven, N., Gastin, I., Choné, L., Hudziak, H., Rhin, B., Delanoë, C., LeFaou, A., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199707243370404 · Cited by 432
Shih, C. M., Lo, S. J., Miyamura, T., Chen, S. Y., & Lee, Y. H. (1993) · Journal of Virology · doi:10.1128/jvi.67.10.5823-5832.1993 · Cited by 332
Metadata
- Authors
- Kato, N., Hijikata, M., Ootsuyama, Y., Nakagawa, M., Ohkoshi, S., Sugimura, T., & Shimotohno, K.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1990-12
- Volume
- 87
- Issue
- 24
- Pages
- 9524-9528
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1971792395
- Cited by
- 1,191
- References
- 0
- FWCI
- 52.84
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis. https://app.cochat.ai/papers/10.1073/pnas.87.24.9524
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- Kato, N., Hijikata, M., Ootsuyama, Y., Nakagawa, M., Ohkoshi, S., Sugimura, T., & Shimotohno, K. (1990). Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.87.24.9524
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