The DOI matches its Crossref record.
HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24.
Open accessAbstract
A common chromosomal abnormality in childhood T-cell acute leukemia is a translocation, t(10;14) (q24;q11), that together with the variant t(7;10)(q35;q24) is present in up to 7% of this tumor type. The gene adjacent to the 10q24 region is transcriptionally activated after translocation to either TCRD (14q11) or TCRB (7q35). It encodes a homeobox gene closely related to the developmentally regulated homeotic genes of flies and mammals. The coding capacity of this activated gene, designated HOX11, is undisturbed in a T-cell line carrying the translocation t(7;10)(q35;q24). Therefore, the HOX11 homeobox gene seems to be involved in T-cell tumorigenesis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Chromosomal translocations in human cancer
Rabbitts, T. H. (1994) · Nature · doi:10.1038/372143a0 · Cited by 1,503
Self-citationChromosome Aberrations and Cancer
Solomon, E., Borrow, J., & Goddard, A. D. (1991) · Science · doi:10.1126/science.1957167 · Cited by 584
Rabbitts, T. H., Forster, A., Larson, R., & Nathan, P. (1993) · Nature Genetics · doi:10.1038/ng0693-175 · Cited by 554
Self-citationThe molecular basis of T cell acute lymphoblastic leukemia
Van Vlierberghe, P., & Ferrando, A. (2012) · Journal of Clinical Investigation · doi:10.1172/jci61269 · Cited by 488
Non-Hodgkin's Lymphoma in Childhood
Sandlund, J. T., Downing, J. R., & Crist, W. M. (1996) · New England Journal of Medicine · doi:10.1056/nejm199605093341906 · Cited by 443
Metadata
- Authors
- Kennedy, M. A., Gonzalez-Sarmiento, R., Kees, U. R., Lampert, F., Dear, N., Boehm, T., & Rabbitts, T. H.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1991-10-15
- Volume
- 88
- Issue
- 20
- Pages
- 8900-8904
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1991962475
- Cited by
- 250
- References
- 0
- FWCI
- 22.62
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24. https://app.cochat.ai/papers/10.1073/pnas.88.20.8900
- The paper
- Kennedy, M. A., Gonzalez-Sarmiento, R., Kees, U. R., Lampert, F., Dear, N., Boehm, T., & Rabbitts, T. H. (1991). HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.88.20.8900
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
