The DOI matches its Crossref record; 125 of the 125 references it cites were found in a registry or an index.
The molecular basis of T cell acute lymphoblastic leukemia
Open accessAbstract
T cell acute lymphoblastic leukemias (T-ALLs) arise from the malignant transformation of hematopoietic progenitors primed toward T cell development, as result of a multistep oncogenic process involving constitutive activation of NOTCH signaling and genetic alterations in transcription factors, signaling oncogenes, and tumor suppressors. Notably, these genetic alterations define distinct molecular groups of T-ALL with specific gene expression signatures and clinicobiological features. This review summarizes recent advances in our understanding of the molecular genetics of T-ALL.
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Cites
Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
Weng, A. P., Ferrando, A. A., Lee, W., Morris, J. P., Silverman, L. B., Sanchez-Irizarry, C., Blacklow, S. C., Look, A. T., & Aster, J. C. (2004) · Science · doi:10.1126/science.1102160 · Cited by 2,715
Self-citationGenome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
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The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
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“ETV6 mutations encoding truncated proteins with dominant-negative activity are frequently found in early immature T-ALLs (32, 33).”
InfluentialPui, C.-H., Robison, L. L., & Look, A. T. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60457-2 · Cited by 1,564
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Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis
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Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
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Self-citationEarly T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia
Coustan-Smith, E., Mullighan, C. G., Onciu, M., Behm, F. G., Raimondi, S. C., Pei, D., Cheng, C., Su, X., Rubnitz, J. E., Basso, G., et al. (2009) · The Lancet Oncology · doi:10.1016/s1470-2045(08)70314-0 · Cited by 1,019
Cited by
Activation of proto-oncogenes by disruption of chromosome neighborhoods
Hnisz, D., Weintraub, A. S., Day, D. S., Valton, A.-L., Bak, R. O., Li, C. H., Goldmann, J., Lajoie, B. R., Fan, Z. P., Sigova, A. A., et al. (2016) · Science · doi:10.1126/science.aad9024 · Cited by 1,042
“The LMO2 gene encodes a transcription factor that is overexpressed and oncogenic in some forms of T-ALL (14, 20).”
BackgroundMalard, F., & Mohty, M. (2020) · The Lancet · doi:10.1016/s0140-6736(19)33018-1 · Cited by 773
Winter, G. E., Mayer, A., Buckley, D. L., Erb, M. A., Roderick, J. E., Vittori, S., Reyes, J. M., di Iulio, J., Souza, A., Ott, C. J., et al. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.06.004 · Cited by 465
De Keersmaecker, K., Atak, Z. K., Li, N., Vicente, C., Patchett, S., Girardi, T., Gianfelici, V., Geerdens, E., Clappier, E., Porcu, M., et al. (2013) · Nature Genetics · doi:10.1038/ng.2508 · Cited by 428
Herranz, D., Ambesi-Impiombato, A., Palomero, T., Schnell, S. A., Belver, L., Wendorff, A. A., Xu, L., Castillo-Martin, M., Llobet-Navás, D., Cordon-Cardo, C., et al. (2014) · Nature Medicine · doi:10.1038/nm.3665 · Cited by 405
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Metadata
- Authors
- Van Vlierberghe, P., & Ferrando, A.
- Venue
- Journal of Clinical Investigation
- Published
- 2012-10-01
- Volume
- 122
- Issue
- 10
- Pages
- 3398-3406
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W2007240193
- Cited by
- 488
- References
- 125
- FWCI
- 35.59
- Type
- journal article
- Language
- en
- Open access
- bronze
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