The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Antigenic variation in Plasmodium falciparum.
Open accessAbstract
Antigenic variation of infectious organisms is a major factor in evasion of the host immune response. However, there has been no definitive demonstration of this phenomenon in the malaria parasite Plasmodium falciparum. In this study, cloned parasites were examined serologically and biochemically for the expression of erythrocyte surface antigens. A cloned line of P. falciparum gave rise to progeny that expressed antigenically distinct forms of an erythrocyte surface antigen but were otherwise identical. This demonstrates that antigenic differences on the surface of P. falciparum-infected erythrocytes can arise by antigenic variation of clonal parasite populations. The antigenic differences were shown to result from antigenic variation of the parasite-encoded protein, the P. falciparum erythrocyte membrane protein 1.
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Cites
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Rapid switching to multiple antigenic and adhesive phenotypes in malaria
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Cited by
Su, X.-Z., Heatwole, V. M., Wertheimer, S. P., Guinet, F., Herrfeldt, J. A., Peterson, D. S., Ravetch, J. A., & Wellems, T. E. (1995) · Cell · doi:10.1016/0092-8674(95)90055-1 · Cited by 1,219
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The Biology of Avian Eimeria with an Emphasis on their Control by Vaccination
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An Epigenetic Signature for Monoallelic Olfactory Receptor Expression
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Metadata
- Authors
- Biggs, B. A., Goozé, L., Wycherley, K., Wollish, W., Southwell, B., Leech, J. H., & Brown, G. V.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1991-10-15
- Volume
- 88
- Issue
- 20
- Pages
- 9171-9174
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2094649888
- Cited by
- 505
- References
- 10
- FWCI
- 9.25
- Type
- journal article
- Language
- en
- Open access
- green
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- Biggs, B. A., Goozé, L., Wycherley, K., Wollish, W., Southwell, B., Leech, J. H., & Brown, G. V. (1991). Antigenic variation in Plasmodium falciparum. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.88.20.9171
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