The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Two members of a widely expressed subfamily of hormone-stimulated adenylyl cyclases.
Open accessAbstract
cDNA encoding a hormone- and guanine nucleotide-stimulated adenylyl cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] (type 6) from rat liver and kidney has been cloned and expressed. This enzyme is stimulated by forskolin, guanosine 5'-[gamma-thio]triphosphate, and isoproterenol plus GTP but is not stimulated by beta gamma subunits of guanine nucleotide-binding proteins. A second form (type 5), which is 75% similar to type 6, has also been cloned. Both types 5 and 6 cDNAs have multiple messages. PCR-based detection of the mRNA for the type 5 and 6 enzymes indicates that both are widely distributed. Homology analyses indicate at least four distinct subfamilies of guanine nucleotide stimulatory protein-regulated adenylyl cyclases. Types 5 and 6 enzymes define one distinct subfamily of mammalian adenylyl cyclases. Diversity of one guanine nucleotide-binding protein-regulated effector may allow different modes of regulation of cell-surface signal transmission.
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Citations
Cites
Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ Subunits
Tang, W.-J., & Gilman, A. G. (1991) · Science · doi:10.1126/science.1962211 · Cited by 1,091
Cloning and expression of a Ca(2+)-inhibitable adenylyl cyclase from NCB-20 cells.
Yoshimura, M., & Cooper, D. M. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.15.6716 · Cited by 268
Katsushika, S., Chen, L., Kawabe, J., Nilakantan, R., Halnon, N. J., Homcy, C. J., & Ishikawa, Y. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.18.8774 · Cited by 209
Cited by
Complexity and Diversity of Mammalian Adenylyl Cyclases
Sunahara, R. K., Dessauer, C. W., & Gilman, A. G. (1996) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pa.36.040196.002333 · Cited by 874
Mammalian Membrane-bound Adenylyl Cyclases
Taussig, R., & Gilman, A. G. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.1.1 · Cited by 721
Adenylyl cyclases and the interaction between calcium and cAMP signalling
Cooper, D. M. F., Mons, N., & Karpen, J. W. (1995) · Nature · doi:10.1038/374421a0 · Cited by 600
Cali, J. J., Zwaagstra, J. C., Mons, N., Cooper, D. M., & Krupinski, J. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)32700-x · Cited by 363
Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases.
Taussig, R., Tang, W. J., Hepler, J. R., & Gilman, A. G. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)37574-9 · Cited by 354
Metadata
- Authors
- Premont, R. T., Chen, J., Ma, H. W., Ponnapalli, M., & Iyengar, R.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1992-10-15
- Volume
- 89
- Issue
- 20
- Pages
- 9809-9813
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2031916898
- Cited by
- 178
- References
- 3
- FWCI
- 6.36
- Type
- journal article
- Language
- en
- Open access
- green
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