The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Elimination of paternal mitochondrial DNA in intraspecific crosses during early mouse embryogenesis.
Open accessAbstract
To examine whether mtDNA is uni- or biparentally transmitted in mice, we developed an assay that can detect sperm mtDNA in a single mouse embryo. In intraspecific hybrids of Mus musculus, paternal mtDNA was detected only through the early pronucleus stage, and its disappearance co-incided with loss of membrane potential in sperm-derived mitochondria. By contrast, in interspecific hybrids between M. musculus and Mus spretus, paternal mtDNA was detected throughout development from pronucleus stage to neonates. We propose that oocyte cytoplasm has a species-specific mechanism that recognizes and eliminates sperm mitochondria and mtDNA. This mechanism must recognize nuclearly encoded proteins in the sperm midpiece, and not the mtDNA or the proteins it encodes, because sperm mitochondria from the congenic strain B6.mtspr, which carries M. spretus mtDNA on background of M. musculus (B6) nuclear genes, were eliminated early by B6 oocytes as in intraspecific crosses. We conclude that cytoplasmic genomes are transmitted uniparentally in intraspecific crosses in mammals as in Chlamydomonas and that leakage of parental mtDNA is limited to interspecific crosses, which rarely occur in nature.
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Cites
Manipulating the mouse embryo: A laboratory manual
Hogan, B. L. M., Costantini, F. D., & Lacy, E. (1986) · Cited by 4,460
Sequence and gene organization of mouse mitochondrial DNA
Bibb, M. J., Van Etten, R. A., Wright, C. T., Walberg, M. W., & Clayton, D. A. (1981) · Cell · doi:10.1016/0092-8674(81)90300-7 · Cited by 1,710
Localization of mitochondria in living cells with rhodamine 123.
Johnson, L. V., Walsh, M. L., & Chen, L. B. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.2.990 · Cited by 1,553
Gichner, T. (1982) · Biologia Plantarum · doi:10.1007/bf02909099 · Cited by 1,181
Paternal inheritance of mitochondrial DNA in mice
Gyllensten, U., Wharton, D., Josefsson, A., & Wilson, A. C. (1991) · Nature · doi:10.1038/352255a0 · Cited by 673
An unusual type of mitochondrial DNA inheritance in the blue mussel Mytilus.
Zouros, E., Oberhauser Ball, A., Saavedra, C., & Freeman, K. R. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.16.7463 · Cited by 427
Loveland, B. (1990) · Cell · doi:10.1016/0092-8674(90)90345-f · Cited by 320
Ball, E. H., & Singer, S. J. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.1.123 · Cited by 265
Incomplete maternal transmission of mitochondrial DNA in Drosophila.
Kondo, R., Satta, Y., Matsuura, E. T., Ishiwa, H., Takahata, N., & Chigusa, S. I. (1990) · Genetics · doi:10.1093/genetics/126.3.657 · Cited by 248
Number of mitochondria and some properties of mitochondrial DNA in the mouse egg
Pikó, L., & Matsumoto, L. (1976) · Developmental Biology · doi:10.1016/0012-1606(76)90253-0 · Cited by 243
Cited by
The mitochondrial genome: structure, transcription, translation and replication
Taanman, J.-W. (1999) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(98)00161-3 · Cited by 1,635
Transcriptional paradigms in mammalian mitochondrial biogenesis and function
Scarpulla, R. C. (2008) · Physiological Reviews · doi:10.1152/physrev.00025.2007 · Cited by 1,666
ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis
Ishikawa, K., Takenaga, K., Akimoto, M., Koshikawa, N., Yamaguchi, A., Imanishi, H., Nakada, K., Honma, Y., & Hayashi, J.-I. (2008) · Science · doi:10.1126/science.1156906 · Cited by 1,444
Self-citationUniparental inheritance of mitochondrial and chloroplast genes: mechanisms and evolution.
Birky, C. W. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.25.11331 · Cited by 969
Transcriptional integration of mitochondrial biogenesis
Scarpulla, R. C., Vega, R. B., & Kelly, D. P. (2012) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2012.06.006 · Cited by 798
Metadata
- Authors
- Kaneda, H., Hayashi, J., Takahama, S., Taya, C., Lindahl, K. F., & Yonekawa, H.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1995-05-09
- Volume
- 92
- Issue
- 10
- Pages
- 4542-4546
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1981161568
- Cited by
- 462
- References
- 24
- FWCI
- 20.37
- Type
- journal article
- Language
- en
- Open access
- green
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- Kaneda, H., Hayashi, J., Takahama, S., Taya, C., Lindahl, K. F., & Yonekawa, H. (1995). Elimination of paternal mitochondrial DNA in intraspecific crosses during early mouse embryogenesis. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.92.10.4542
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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