The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Redistribution of phosphatidylethanolamine at the cleavage furrow of dividing cells during cytokinesis
Open accessAbstract
Ro09-0198 is a tetracyclic polypeptide of 19 amino acids that recognizes strictly the structure of phosphatidylethanolamine (PE) and forms a tight equimolar complex with PE on biological membranes. Using the cyclic peptide coupled with fluorescence-labeled streptavidin, we have analyzed the cell surface localization of PE in dividing Chinese hamster ovary cells. We found that PE was exposed on the cell surface specifically at the cleavage furrow during the late telophase of cytokinesis. PE was exposed on the cell surface only during the late telophase and no alteration in the distribution of the plasma membrane-bound cyclic peptide was observed during the cytokinesis, suggesting that the surface exposure of PE reflects the enhanced scrambling of PE at the cleavage furrow. Furthermore, cell surface immobilization of PE induced by adding the cyclic peptide coupled with streptavidin to prometaphase cells effectively blocked the cytokinesis at late telophase. The peptide-streptavidin complex treatment had no effect on furrowing, rearrangement of microtubules, and nuclear reconstitution, but specifically inhibited both actin filament disassembly at the cleavage furrow and subsequent membrane fusion. These results suggest that the redistribution of the plasma membrane phospholipids is a crucial step for cytokinesis and the cell surface PE may play a pivotal role in mediating a coordinate movement between the contractile ring and plasma membrane to achieve successful cell division.
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S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function
Hoyt, M. A., Totis, L., & Roberts, B. T. (1991) · Cell · doi:10.1016/0092-8674(81)90014-3 · Cited by 1,131
Effects of Cytochalasins on Mammalian Cells
CARTER, S. B. (1967) · Nature · doi:10.1038/213261a0 · Cited by 948
Phospholipids in animal eukaryotic membranes: transverse asymmetry and movement
Zachowski, A. (1993) · Biochemical Journal · doi:10.1042/bj2940001 · Cited by 856
Lipid regulation of cell membrane structure and function
Yèagle, P. L. (1989) · The FASEB Journal · doi:10.1096/fasebj.3.7.2469614 · Cited by 513
Zwaal, R. F. A., Roelofsen, B., Comfurius, P., & van Deenen, L. L. M. (1975) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(75)90044-9 · Cited by 359
Transbilayer movement of phospholipids in red cell and platelet membranes
Schroit, A. J., & Zwaal, R. F. A. (1991) · Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes · doi:10.1016/0304-4157(91)90019-s · Cited by 313
Membrane fusion and inverted phases
Ellens, H., Siegel, D. P., Alford, D., Yeagle, P. L., Boni, L., Lis, L. J., Quinn, P. J., & Bentz, J. (1989) · Biochemistry · doi:10.1021/bi00435a011 · Cited by 311
Satterwhite, L. L., & Pollard, T. D. (1992) · Current Opinion in Cell Biology · doi:10.1016/0955-0674(92)90057-j · Cited by 243
A guide to the use of pore-forming toxins for controlled permeabilization of cell membranes
Bhakdi, S., Weller, U., Walev, I., Martin, E., Jonas, D., & Palmer, M. (1993) · Medical Microbiology and Immunology · doi:10.1007/bf00219946 · Cited by 230
Zimmerberg, J., Vogel, S. S., & Chernomordik, L. V. (1993) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.bb.22.060193.002245 · Cited by 202
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Area‐Gomez, E., del Carmen Lara Castillo, M., Tambini, M. D., Guardia‐Laguarta, C., de Groof, A. J. C., Madra, M., Ikenouchi, J., Umeda, M., Bird, T. D., Sturley, S. L., et al. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.202 · Cited by 638
Self-citationPhosphatidylethanolamine Metabolism in Health and Disease
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Vance, J. E., & Tasseva, G. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2012.08.016 · Cited by 521
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Escribá, P. V., González‐Ros, J. M., Goñi, F. M., Kinnunen, P. K. J., Vigh, L., Sánchez‐Magraner, L., Fernández, A. M., Busquets, X., Horváth, I., & Barceló‐Coblijn, G. (2008) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2008.00281.x · Cited by 454
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Metadata
- Authors
- Emoto, K., Kobayashi, T., Yamaji, A., Aizawa, H., Yahara, I., Inoue, K., & Umeda, M.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1996-11-12
- Volume
- 93
- Issue
- 23
- Pages
- 12867-12872
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W1986648162
- Cited by
- 268
- References
- 25
- FWCI
- 1.77
- Type
- journal article
- Language
- en
- Open access
- green
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- Emoto, K., Kobayashi, T., Yamaji, A., Aizawa, H., Yahara, I., Inoue, K., & Umeda, M. (1996). Redistribution of phosphatidylethanolamine at the cleavage furrow of dividing cells during cytokinesis. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.93.23.12867
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