The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Clustering of meiotic double-strand breaks on yeast chromosome III
Open accessAbstract
In the yeast Saccharomyces cerevisiae , meiotic recombination is initiated by transient DNA double-strand breaks (DSBs) that are repaired by interaction of the broken chromosome with its homologue. To identify a large number of DSB sites and gain insight into the control of DSB formation at both the local and the whole chromosomal levels, we have determined at high resolution the distribution of meiotic DSBs along the 340 kb of chromosome III. We have found 76 DSB regions, mostly located in intergenic promoter-containing intervals. The frequency of DSBs varies at least 50-fold from one region to another. The global distribution of DSB regions along chromosome III is nonrandom, defining large (39–105 kb) chromosomal domains, both hot and cold. The distribution of these localized DSBs indicates that they are likely to initiate most crossovers along chromosome III, but some discrepancies remain to be explained.
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Goffeau, A., Barrell, B. G., Bussey, H., Davis, R. W., Dujon, B., Feldmann, H., Galibert, F., Hoheisel, J. D., Jacq, C., Johnston, M., et al. (1996) · Science · doi:10.1126/science.274.5287.546 · Cited by 4,263
The complete DNA sequence of yeast chromosome III
Oliver, S. G., van der Aart, Q. J. M., Agostoni-Carbone, M. L., Aigle, M., Alberghina, L., Alexandraki, D., Antoine, G., Anwar, R., Ballesta, J. P. G., Benit, P., et al. (1992) · Nature · doi:10.1038/357038a0 · Cited by 843
Alani, E., Padmore, R., & Kleckner, N. (1990) · Cell · doi:10.1016/0092-8674(90)90524-i · Cited by 597
Double-strand breaks at an initiation site for meiotic gene conversion
Sun, H., Treco, D., Schultes, N. P., & Szostak, J. W. (1989) · Nature · doi:10.1038/338087a0 · Cited by 524
Gotta, M., Laroche, T., Formenton, A., Maillet, L., Scherthan, H., & Gasser, S. M. (1996) · The Journal of cell biology · doi:10.1083/jcb.134.6.1349 · Cited by 465
Padmore, R., Cao, L., & Kleckner, N. (1991) · Cell · doi:10.1016/0092-8674(91)90046-2 · Cited by 444
Meiosis-Induced Double-Strand Break Sites Determined by Yeast Chromatin Structure
Wu, T.-C., & Lichten, M. (1994) · Science · doi:10.1126/science.8290959 · Cited by 443
The Role of the Genome Project in Determining Gene Function: Insights from Model Organisms
Miklos, G. L. G., & Rubin, G. M. (1996) · Cell · doi:10.1016/s0092-8674(00)80126-9 · Cited by 440
Kleckner, N. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.16.8167 · Cited by 413
MEIOTIC RECOMBINATION HOTSPOTS
Lichten, M., & Goldman, A. S. H. (1995) · Annual Review of Genetics · doi:10.1146/annurev.ge.29.120195.002231 · Cited by 375
Cited by
Capturing Chromosome Conformation
Dekker, J., Rippe, K., Dekker, M., & Kleckner, N. (2002) · Science · doi:10.1126/science.1067799 · Cited by 3,652
Multiple Pathways of Recombination Induced by Double-Strand Breaks in Saccharomyces cerevisiae
Pâques, F., & Haber, J. E. (1999) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.63.2.349-404.1999 · Cited by 2,120
Meiotic Chromosomes: Integrating Structure and Function
Zickler, D., & Kleckner, N. (1999) · Annual Review of Genetics · doi:10.1146/annurev.genet.33.1.603 · Cited by 1,255
Jeffreys, A. J., Kauppi, L., & Neumann, R. (2001) · Nature Genetics · doi:10.1038/ng1001-217 · Cited by 835
Hunter, N., & Kleckner, N. (2001) · Cell · doi:10.1016/s0092-8674(01)00430-5 · Cited by 658
Metadata
- Authors
- Baudat, F., & Nicolas, A.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1997-05-13
- Volume
- 94
- Issue
- 10
- Pages
- 5213-5218
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2090293826
- Cited by
- 320
- References
- 36
- FWCI
- 6.08
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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