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Cited by 431

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Mechanical separation of the complementary strands of DNA

Open access
Essevaz-Roulet, B., Bockelmann, U., Heslot, F.·1997·Proceedings of the National Academy of Sciences

Abstract

We describe the mechanical separation of the two complementary strands of a single molecule of bacteriophage λ DNA. The 3′ and 5′ extremities on one end of the molecule are pulled progressively apart, and this leads to the opening of the double helix. The typical forces along the opening are in the range of 10–15 pN. The separation force signal is shown to be related to the local GC vs. AT content along the molecule. Variations of this content on a typical scale of 100–500 bases are presently detected.

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Crossref · 10.1073/pnas.94.22.11935

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Metadata

Authors
Essevaz-Roulet, B., Bockelmann, U., & Heslot, F.
Venue
Proceedings of the National Academy of Sciences
Published
1997-10-28
Volume
94
Issue
22
Pages
11935-11940
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W2122708630
Cited by
431
References
2
FWCI
11.78
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Mechanical separation of the complementary strands of DNA. https://app.cochat.ai/papers/10.1073/pnas.94.22.11935
The paper
Essevaz-Roulet, B., Bockelmann, U., & Heslot, F. (1997). Mechanical separation of the complementary strands of DNA. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.94.22.11935

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.