The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Life without DNA repair
Open accessAbstract
The advent of gene targeting techniques has permitted the construction of specific genetic deficiencies to evaluate the biological contribution(s) of an individual protein. Mice lacking a precise DNA repair activity have been generated, and these mutants show various combinations of defective embryogenesis, tissue-specific dysfunction, hypersensitivity to DNA-damaging agents, premature senescence, genetic instability, and elevated cancer rates (1). That repair-deficient animals display such abnormalities underscores the fundamental importance of DNA repair in protecting against the mutagenic and cytotoxic effects of DNA damage.
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Citations
Cites
Instability and decay of the primary structure of DNA
Lindahl, T. (1993) · Nature · doi:10.1038/362709a0 · Cited by 5,679
Excision of Deoxyribose Phosphate Residues by DNA Polymerase β During DNA Repair
Matsumoto, Y., & Kim, K. (1995) · Science · doi:10.1126/science.7624801 · Cited by 683
Cited by
Genome maintenance mechanisms for preventing cancer
Hoeijmakers, J. H. J. (2001) · Nature · doi:10.1038/35077232 · Cited by 3,939
Masson, M., Niedergang, C., Schreiber, V., Muller, S., Menissier-de Murcia, J., & de Murcia, G. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.6.3563 · Cited by 910
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
Klungland, A., Rosewell, I., Hollenbach, S., Larsen, E., Daly, G., Epe, B., Seeberg, E., Lindahl, T., & Barnes, D. E. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13300 · Cited by 807
Mechanisms of DNA double-strand break repair and their potential to induce chromosomal aberrations
Pfeiffer, P. (2000) · Mutagenesis · doi:10.1093/mutage/15.4.289 · Cited by 462
The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA
Wilson, D. M., & Barsky, D. (2001) · Mutation Research/DNA Repair · doi:10.1016/s0921-8777(01)00063-5 · Cited by 408
Self-citation
Metadata
- Authors
- Wilson, D. M., & Thompson, L. H.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1997-11-25
- Volume
- 94
- Issue
- 24
- Pages
- 12754-12757
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2098041196
- Cited by
- 233
- References
- 2
- FWCI
- 6.41
- Type
- journal article
- Language
- en
- Open access
- green
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- Wilson, D. M., & Thompson, L. H. (1997). Life without DNA repair. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.94.24.12754
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.