The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Genomic evidence for two functionally distinct gene classes
Open accessAbstract
Analyses of complete genomes indicate that a massive prokaryotic gene transfer (or transfers) preceded the formation of the eukaryotic cell. In comparisons of the entire set of Methanococcus jannaschii genes with their orthologs from Escherichia coli , Synechocystis 6803 , and the yeast Saccharomyces cerevisiae , it is shown that prokaryotic genomes consist of two different groups of genes. The deeper, diverging informational lineage codes for genes which function in translation, transcription, and replication, and also includes GTPases, vacuolar ATPase homologs, and most tRNA synthetases. The more recently diverging operational lineage codes for amino acid synthesis, the biosynthesis of cofactors, the cell envelope, energy metabolism, intermediary metabolism, fatty acid and phospholipid biosynthesis, nucleotide biosynthesis, and regulatory functions. In eukaryotes, the informational genes are most closely related to those of Methanococcus , whereas the majority of operational genes are most closely related to those of Escherichia , but some are closest to Methanococcus or to Synechocystis .
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Iwabe, N., Kuma, K., Hasegawa, M., Osawa, S., & Miyata, T. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.23.9355 · Cited by 902
An ancestral mitochondrial DNA resembling a eubacterial genome in miniature
Lang, B. F., Burger, G., O'Kelly, C. J., Cedergren, R., Golding, G. B., Lemieux, C., Sankoff, D., Turmel, M., & Gray, M. W. (1997) · Nature · doi:10.1038/387493a0 · Cited by 620
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Doolittle, W. F. (1999) · Science · doi:10.1126/science.284.5423.2124 · Cited by 1,888
Complex archaea that bridge the gap between prokaryotes and eukaryotes
Spang, A., Saw, J. H., Jørgensen, S. L., Zaremba-Niedzwiedzka, K., Martijn, J., Lind, A. E., van Eijk, R., Schleper, C., Guy, L., & Ettema, T. J. G. (2015) · Nature · doi:10.1038/nature14447 · Cited by 1,324
Eukaryotic evolution, changes and challenges
Embley, T. M., & Martin, W. (2006) · Nature · doi:10.1038/nature04546 · Cited by 867
Evolutionary Rate in the Protein Interaction Network
Fraser, H. B., Hirsh, A. E., Steinmetz, L. M., Scharfe, C., & Feldman, M. W. (2002) · Science · doi:10.1126/science.1068696 · Cited by 869
Martin, W., & Russell, M. J. (2003) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.2002.1183 · Cited by 856
Metadata
- Authors
- Rivera, M. C., Jain, R., Moore, J. E., & Lake, J. A.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1998-05-26
- Volume
- 95
- Issue
- 11
- Pages
- 6239-6244
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2059123697
- Cited by
- 543
- References
- 2
- FWCI
- 7.09
- Type
- journal article
- Language
- en
- Open access
- green
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- Rivera, M. C., Jain, R., Moore, J. E., & Lake, J. A. (1998). Genomic evidence for two functionally distinct gene classes. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.95.11.6239
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