The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Generation of broad-spectrum disease resistance by overexpression of an essential regulatory gene in systemic acquired resistance
Open accessAbstract
The recently cloned NPR1 gene of Arabidopsis thaliana is a key regulator of acquired resistance responses. Upon induction, NPR1 expression is elevated and the NPR1 protein is activated, in turn inducing expression of a battery of downstream pathogenesis-related genes. In this study, we found that NPR1 confers resistance to the pathogens Pseudomonas syringae and Peronospora parasitica in a dosage-dependent fashion. Overexpression of NPR1 leads to enhanced resistance with no obvious detrimental effect on the plants. Thus, for the first time, a single gene is shown to be a workable target for genetic engineering of nonspecific resistance in plants.
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Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302
Cited by
Durrant, W. E., & Dong, X. (2004) · Annual Review of Phytopathology · doi:10.1146/annurev.phyto.42.040803.140421 · Cited by 3,184
Self-citationSalicylic Acid and its Function in Plant ImmunityF
An, C., & Mou, Z. (2011) · Journal of Integrative Plant Biology · doi:10.1111/j.1744-7909.2011.01043.x · Cited by 517
Regulation of Enteric Endophytic Bacterial Colonization by Plant Defenses
Iniguez, A. L., Dong, Y., Carter, H. D., Ahmer, B. M. M., Stone, J. M., & Triplett, E. W. (2005) · Molecular Plant-Microbe Interactions® · doi:10.1094/mpmi-18-0169 · Cited by 293
Metadata
- Authors
- Cao, H., Li, X., & Dong, X.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 1998-05-26
- Volume
- 95
- Issue
- 11
- Pages
- 6531-6536
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2082498921
- Cited by
- 575
- References
- 1
- FWCI
- 30.29
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Generation of broad-spectrum disease resistance by overexpression of an essential regulatory gene in systemic acquired resistance. https://app.cochat.ai/papers/10.1073/pnas.95.11.6531
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- Cao, H., Li, X., & Dong, X. (1998). Generation of broad-spectrum disease resistance by overexpression of an essential regulatory gene in systemic acquired resistance. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.95.11.6531
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
