The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
Effects of environmental enrichment on gene expression in the brain
Open accessAbstract
An enriched environment is known to promote structural changes in the brain and to enhance learning and memory performance in rodents [Hebb, D. O. (1947)Am. Psychol.2, 306–307]. To better understand the molecular mechanisms underlying these experience-dependent cognitive changes, we have used high-density oligonucleotide microarrays to analyze gene expression in the brain. Expression of a large number of genes changes in response to enrichment training, many of which can be linked to neuronal structure, synaptic plasticity, and transmission. A number of these genes may play important roles in modulating learning and memory capacity.
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Cites
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Self-citationEnvironmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective
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Cited by
Enriched environments, experience-dependent plasticity and disorders of the nervous system
Nithianantharajah, J., & Hannan, A. J. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1970 · Cited by 1,771
Recovery of learning and memory is associated with chromatin remodelling
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Early behavioral intervention, brain plasticity, and the prevention of autism spectrum disorder
Dawson, G. (2008) · Development and Psychopathology · doi:10.1017/s0954579408000370 · Cited by 1,138
VEGF links hippocampal activity with neurogenesis, learning and memory
Cao, L., Jiao, X., Zuzga, D. S., Liu, Y., Fong, D. M., Young, D., & During, M. J. (2004) · Nature Genetics · doi:10.1038/ng1395 · Cited by 850
Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
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Metadata
- Authors
- Rampon, C., Jiang, C. H., Dong, H., Tang, Y.-P., Lockhart, D. J., Schultz, P. G., Tsien, J. Z., & Hu, Y.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2000-11-07
- Volume
- 97
- Issue
- 23
- Pages
- 12880-12884
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2067570041
- Cited by
- 615
- References
- 46
- FWCI
- 10.63
- Type
- journal article
- Language
- en
- Open access
- green
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- Rampon, C., Jiang, C. H., Dong, H., Tang, Y.-P., Lockhart, D. J., Schultz, P. G., Tsien, J. Z., & Hu, Y. (2000). Effects of environmental enrichment on gene expression in the brain. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.97.23.12880
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
