Isolation of a Protein Target of the FKBP12-Rapamycin Complex in Mammalian Cells

Sabers, Candace J., Martin, Mary M., Brunn, Gregory J., Williams, Josie M., Dumont, Francis J., Wiederrecht, Gregory, Abraham, Robert T.·1995·Journal of Biological Chemistry

Cited by (885)

Items 801–885 of 885

  1. ЭКСПРЕССИЯ ГЕНОВ ЖИВОТНЫХ ПРИ АМИНОКИСЛОТНОМ ИМБАЛАНСЕ ЧАСТЬ I GENE EXPRESSION OF ANIMALS IN THE AMINO ACID IMBALANCE Part I
    Ryadchikov Victor Georgievich, Плотников Владимир Константинович · 2013
  2. Major Processes for Muscle Gain and Loss
    2010 · CRC Press eBooks
  3. Xenobiotic-metabolizing enzymes elevated in multiple mouse models of slow aging
    Michael J. Steinbaugh · 2012 · Deep Blue (University of Michigan)
  4. Identification of Novel Cell Cycle Targets Using Small Molecule Ligands
    Vivian Berlin, Maria Isabel Chiu · 1996 · Springer eBooks
  5. The Role of CCL5/CCR5 Signal Transduction in T cell Function and Breast Cancer
    Thomas T. Murooka · 2009 · TSpace (University of Toronto)
  6. mTORC2
    Caroline Treins, Julian Downward · 2010 · The Enzymes
  7. Lymphome du manteau : un modèle biologique et clinique
    Valérie Camara‐Clayette, Olivier Hermine, Vincent Ribrag · 2011 · Encyclopédie médico-chirurgicale. Hématologie
  8. Uncoupling Neuroprotection from Immunosuppression: the Discovery of ILS-920
    Edmund I. Graziani · 2010 · Royal Society of Chemistry eBooks
  9. Targeting mTOR: A Little Bit of History and a Large Future
    Eric Keith Rowinsky · 2015 · Springer eBooks
  10. Structural and molecular characterization of human FK506-binding protein 25 (FKBP25), a nuclear immunophilin
    Ajit Prakash · 2016
  11. Effect of Akt (PKB) on the activity of mammalian target of rapamycin (mTOR)
    Annett Hahn-Windgassen · 2005
  12. TO R: The First 10 Years
    Anja Lorberg, Michael N. Hall · 2004
  13. Endothelial injury in cardiac transplantation : the role of endothelin antagonism and protein kinases.
    Danny Ramzy · 2008 · TSpace (University of Toronto)
  14. Targeting Oncoproteins for Molecular Cancer Therapy
    Joshua E. Allen, Wafik S. El‐Deiry · 2016 · Springer eBooks
  15. New molecular strategies for prevention of fibroproliferative vascular disease
    Nina-Maria Tigerstedt · 2009
  16. Therapeutic Exploitation of Metabolic Checkpoints In Cancer Cells
    Deven Patel · 2017 · CUNY Academic Works (City University of New York)
  17. High-throughput Analysis and Control of the Pluripotent Stem Cell Microenvironment to Interrogate and Direct Cell Fate
    Emanuel Joseph Paul Nazareth · 2015 · TSpace (University of Toronto)
  18. Identifying novel genes involved in amino acid sensing
    Margaret Dayhoff-Brannigan · 2014
  19. In-vitro-Studie zum Einfluss verschiedener Immunsuppressiva auf Gesamt- und Lebendzellzahl, Zelldurchmesser und Menge an Prokollagen Typ I gingivaler Fibroblasten
    Sievers, Lisa · 2017
  20. A ativação constitutiva de mTORC1 em adipócitos aumenta a capacidade oxidativa mitocondrial e reduz a adiposidade visceral em camundongos.
    Juliana Magdalon · 2017 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  21. Profile of Michael N. Hall, 2017 Albert Lasker Basic Medical Research Awardee: Target of rapamycin, cell growth, and translational control
    Nahum Sonenberg · 2017 · Proceedings of the National Academy of Sciences
  22. Overview of renal cell carcinoma pathways and drug targets
    Bernard J. Escudier · 2011
  23. Estudo do papel de mTOR na regulação da atividade de reparo do DNA mitocondrial humano
    Caio Matheus Prates Batalha Faria · 2018 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  24. Cholesterol synthesis requirements in oligodendrocyte development and myelination
    Emily S. Mathews · 2016
  25. Regulation of mTORC1 by homocysteine and its effects on autophagy in human and mouse neuronal tissues
    Khoosheh Khayati · 2017
  26. Crosstalk between mTORC1 and cAMP Signaling
    Kun‐Liang Guan · 2015
  27. Rapamycin-based macrocyclic library development and Equilibrative Nucleoside Transporter 1 (ENT1) inhibition
    Sam Y. Hong · 2016
  28. Identification of Key Genes and Pathways in First Acute Myocardial Infarction Based on Gene Expression Profiling by Bioinformatics Analysis
    Xiao‐Li Xie · 2019
  29. Pten Signaling in Regulatory T Cells and Inflammatory Disease
    Sharad Shrestha · 2016
  30. Mechanisms of sensitization to apoptosis in multiple myeloma.
    Anna Hammarberg · 2007 · KTH Publication Database DiVA (KTH Royal Institute of Technology)
  31. Tissue-specific Stem Cells
    Sudhansu Shekhar Patra · 2020
  32. Analisis funcional de PP2AB55 en ciclo celular, autofagia y transcripcion
    Alicia Uxía Vázquez Bolado · 2020
  33. Mammalian target of rapamycin: Immunosuppressive drugs offer new insights into cell growth regulation
    Robert T. Abraham · 2000 · Birkhäuser Basel eBooks
  34. Faculty Opinions recommendation of Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease.
    Valina Dawson · 2008 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  35. THE EFFECT OF NUTRITION ON LONGEVITY AND FERTILITY IN DIVERSE DROSOPHILA: A TOR-MEDIATED PROCESS
    Tessa E. Steenwinkel · 2021
  36. Faculty Opinions recommendation of mTOR at the nexus of nutrition, growth, ageing and disease.
    Shawn M. Ferguson · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  37. The Greatwall-Endosulfine-PP2A/B55 pathway in Schizosaccharomyces pombe: regulatory mechanisms and roles in cell differentiation and ageing
    Natalia García-Blanco · 2021
  38. Faculty Opinions recommendation of Histone deacetylase 3 suppression increases PH domain and leucine-rich repeat phosphatase (Phlpp)1 expression in chondrocytes to suppress Akt signaling and matrix secretion.
    Frank Beier, Jason Bush · 2013 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  39. mTOR
    John B. Easton, Peter J. Houghton · 2007 · Humana Press eBooks
  40. Mouse models for brain tumor therapy
    Nikki A. Charles, Andrew B. Lassman, Eric C. Holland · 2011 · Elsevier eBooks
  41. Tacrolimus suppresses itch-related response in diet-induced atopic dermatitis model mice by reducing chloroquine-sensitive sensory neurons
    Masanori Fujii, Shota Imahori, Misao Nakayama, Takeshi Nabe, Susumu Ohya · 2022 · Itch
  42. Effect of CLN3-loss-of-function on cellular metabolism and signalling
    Katarzyna Więciorek-Płuciennik · 2022
  43. Dietary restriction, vegetarian diet, and aging intervention
    Maitree Suttajit, Subramanian Thangaleela, Bhagavathi Sundaram Sivamaruthi, Suphachai Charoensin · 2022 · Elsevier eBooks
  44. Molecular genetic abnormalities in patients with T-cell acute lymphoblastic leukemia: a literature review
    Anastasia N. Vasileva, Olga A. Aleshina, Бидерман Белла Вениаминовна, Andrey Borisovich Sudarikov · 2022 · Oncohematology
  45. Clinical Experiences with Drugs Targeting m TOR
    Thomas Elmer Witzig · 2023 · Wiley eBooks
  46. mTOR signaling and autophagy regulation
    Amruta Singh, Sujit K. Bhutia · 2023 · Elsevier eBooks
  47. Regulação da expressão dos genes TSC1 e TSC2 na via de mTORC1
    Fábio Arthur Mateus Conceição · 2024 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  48. Anti-aging Drugs
    Glenda Elaine Bilder, Patricia Brown-O’Hara · 2025 · Springer eBooks
  49. TOR signaling regulates GPCR levels on the plasma membrane and suppresses the Saccharomyces cerevisiae mating pathway
    Nicholas R. Leclerc, Toby M. Dunne, Sudati Shrestha, Cory P. Johnson, Joshua B. Kelley · 2025 · Journal of Biological Chemistry
  50. Anti-aging strategies for dogs
    Jae Ryong Lim, Jee Hyeon Yoon, Ho Jae Han · 2025 · Journal of Veterinary Science
  51. Identification of Novel Signaling Pathways in T Cells Mediated by Protein Kinase C, Carma1, MALT1 and Bcl10
    Kristia S. Hamilton · 2014 · D-Scholarship@Pitt (University of Pittsburgh)
  52. Modulation par le récepteur neurokinine-1du mécanisme d’action des immunosuppresseurs chez les cellules T
    Khadijé Jizi · 2012
  53. Role of the Yeast Ste20 Protein Kinase Ortholog Map4k4 in Adipose Tissue Function: A Dissertation
    Kalyani Guntur · 2011 · The Journal of the American Medical Association (JAMA) Network (American Medical Association)
  54. Deep-mutational scanning libraries using Tiled-Region Exchange mutagenesis
    Kortni Kindree, Claire A. Chochinov, Keerath Bhachu, Yunyi Cheng, Amelia Caron, Molly McDonald, Zaynab Mamai, Alex N. Nguyen Ba · 2026 · G3 Genes Genomes Genetics
  55. Transcriptional control of PPP2CB by YAP1 and TEAD1 mediates AMPK inhibition and mTORC1 activation in vascular smooth muscle cells
    Sanjana Kumariya, Joanna Stuck, Arturo Grano de Oro, Islam Osman · 2026 · iScience
  56. Propriétés régulatrices des cellules dendritiques humaines traitées par l’acide mycophénolique
    Roxane Lemoine · 2009 · theses.fr (ABES)
  57. Homéostasie calcique au cours des évènements précoces de la maturation des cellules dendritiques humaines
    Romain Félix · 2010 · theses.fr (ABES)
  58. Impact des inhibiteurs de la voie mTOR sur la réponse immunitaire T anti-tumorale
    Laurent Beziaud · 2015 · theses.fr (ABES)
  59. Modulation de la dépression synaptique à long terme dans le noyau du tractus solitaire par le statut nutritionnel
    Abdessattar Khlaifia · 2015 · theses.fr (ABES)
  60. Signalisation CD95/CD95L : implications dans le Lupus Erythémateux Systémique et développement d'outils thérapeutiques ciblés
    Amanda Poissonnier · 2017 · theses.fr (ABES)
  61. Intégration de l’analyse de l’immunomodulation induite par les inhibiteurs de mTOR dans leur développement en cancérologie
    Laura Mansi · 2017 · theses.fr (ABES)
  62. Tuberous sclerosis complex : molecular target of mTORC1 and the role of S6Ks
    Martina Bonucci · 2019 · theses.fr (ABES)
  63. Etude du métabolisme des lymphocytes T CD4+ Foxp3+ régulateurs à l’homéostasie et dans un contexte inflammatoire
    Jordane Divoux · 2019 · theses.fr (ABES)
  64. Modulation de l'autophagie neuronale par la sérine protéase tPA en conditions ischémiques
    Audrey M. Thiebaut · 2019 · theses.fr (ABES)
  65. Exploring the Role of Intercellular and Intracellular Signaling in the Sustenance of Glioblastoma Stem-like Cells
    Kathryn Jacobs · 2020 · theses.fr (ABES)
  66. Biochemical characterization of mTORC1 regulation by glutamine metabolism
    Clément Bodineau · 2020 · theses.fr (ABES)
  67. Rôle de la protéine RICTOR dans le développement des mélanomes
    Ahlem Jebali · 2020 · theses.fr (ABES)
  68. La fonction suppresseur de tumeur de la protéine adaptatrice SLAP dans le cancer colorectal implique la régulation de la signalisation mTORC2
    Rudy Mevizou · 2021 · theses.fr (ABES)
  69. Control of ependymal cell differentiation by the mTOR signaling pathway
    Ayush Srivastava · 2021 · theses.fr (ABES)
  70. Régulation de cohésine par le complexe TORC1 chez la levure Schizosaccharomyces pombe
    Dorian Besson · 2024 · theses.fr (ABES)
  71. La régénération du système nerveux périphérique et central par la voie RSK-RPS6
    Charlotte Decourt · 2023 · theses.fr (ABES)
  72. mTORシグナル伝達経路のBAG6による調節機構
    Fumiaki NISHIUE · Institutional Repositories DataBase (IRDB)
  73. Diet-dependent, beneficial and adverse effects of rapamycin on life span of Drosophila melanogaster
    Lauren N. Jackson, Azriel M. Boles, Caitlyn T. Frye, Isha A. Patel, Robin J. Mockett · 2026 · GeroScience
  74. mTOR-Mediated Neuron–Cancer Interactions
    Joel Karikari Nyarkoh, Matthew J Wolan, David M. Feliciano · 2026 · Kinases and Phosphatases
  75. Rapamycin across biology and medicine: From molecular mechanisms to clinical and translational frontiers
    Lyvia Neves Rebello Alves, Eldamária de Vargas Wolfgramm dos Santos, Raquel Silva dos Reis Trabach, Débora Dummer Meira, Iúri Drumond Louro · 2026 · Biochimica et Biophysica Acta (BBA) - General Subjects
  76. BindingDB Entry 50035034: Cleavage of the cyclohexyl-subunit of rapamycin results in loss of immunosuppressive activity.
    BindingDB · 2012 · UC San Diego
  77. BindingDB Entry 50020515: Optimization of mTOR Inhibitors Using Property-Based Drug Design and Free-Wilson Analysis for Improved In Vivo Efficacy.
    BindingDB · 2024 · UC San Diego
  78. BindingDB Entry 50019164: Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors.
    BindingDB · 2024 · UC San Diego
  79. BindingDB Entry 50047992: Development, synthesis and structure-activity-relationships of inhibitors of the macrophage infectivity potentiator (Mip) proteins of Legionella pneumophila and Burkholderia pseudomallei.
    BindingDB · 2018 · UC San Diego
  80. BindingDB Entry 50015607: Recent advances in development of hetero-bivalent kinase inhibitors.
    BindingDB · 2023 · UC San Diego
  81. BindingDB Entry 50018379: Research progress of mTOR inhibitors.
    BindingDB · 2024 · UC San Diego
  82. Classical autophagy-modulating compounds impair viability and alter autophagy gene expression in schistosomula and adult Schistosoma mansoni
    Agatha Fischer-Carvalho, Larissa Carolina Lopes-Jesus, Sergio Verjovski‐Almeida, Murilo Sena Amaral · 2026 · Frontiers in Parasitology
  83. Autophagy and Necroptosis in Cancer
    Ming Tan, Heng Kean Tan, Ahmed Ismail Hassan Moad, Tengku Sifzizul Tengku Muhammad · 2014 · Springer eBooks
  84. Novel Regulation of mTOR Complex 1 Signaling by Site-Specific mTOR Phosphorylation.
    Bilgen Ekim Üstünel · 2012 · Deep Blue (University of Michigan)
  85. Mechanisms of NOTCH1 Mediated Leukemogenesis: A Dissertation
    Kathleen Cullion · 2009 · eScholarship@UMassChan