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Cited by 289

The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.

Tissue Distribution of the Four Gene Products of the Plasma Membrane Ca2+ Pump

Open access
Stauffer, Thomas P., Guerini, Danilo, Carafoli, Ernesto·1995·Journal of Biological Chemistry

Abstract

Antibodies against the four isoforms of the human plasma membrane Ca(2+)-ATPase (PMCA) were raised using an N-terminal sequence of the pump as epitope. The antibodies against PMCA isoforms 1, 2, and 3 were not species-specific, e.g. they also recognized the corresponding proteins in rat, whereas that against the human PMCA isoform 4 failed to do so. The tissue distribution of the four isoforms was estimated by Western blot analysis. Two, PMCA1 and PMCA4, were expressed in all tissues tested (with the exception of the choroid plexus, where the former was not detected). In most tissues the signal from the PMCA1 protein exceeded that of PMCA4, the exception being the erythrocyte. The PMCA2 and PMCA3 proteins were only found in neuronal tissues; the PMCA2 protein was present in high concentrations in the cerebellum and in the cerebral cortex. At variance with previous results on mRNA (e.g. the kidney) no other tissues contained the PMCA2 protein. PMCA3 was the other tissue-specific isoform; in agreement with results in the rat, the protein was found in human neuronal tissues, particularly in the choroid plexus, but was practically absent in all other tissues tested.

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Crossref · 10.1074/jbc.270.20.12184

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Metadata

Authors
Stauffer, T. P., Guerini, D., & Carafoli, E.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
1995-05
Volume
270
Issue
20
Pages
12184-12190
ISSN
0021-9258 (ISSN-L)
OpenAlex
W2007346353
Cited by
289
References
25
FWCI
6.51
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Tissue Distribution of the Four Gene Products of the Plasma Membrane Ca2+ Pump. https://app.cochat.ai/papers/10.1074/jbc.270.20.12184
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Stauffer, T. P., Guerini, D., & Carafoli, E. (1995). Tissue Distribution of the Four Gene Products of the Plasma Membrane Ca2+ Pump. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.270.20.12184

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.